Ruprecht-Karls-Universität Heidelberg
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Molekulare Biologie der Pflanzen

Dr. Anna Speiser

Dr. Anna Speiser
Dr. Anna Speiser

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The essential amino acid cysteine plays a pivotal role in living organisms. Plants, algae, bacteria and fungi are able to reduce the environmentally available sulphur to produce cysteine. However animals and humans are not able to do so and rely on their nutrition, rely on plants. This is one reason why it is fascinating to me to lay my focus of research on the cysteine biosynthesis pathway in model organism Arabidopsis thaliana. The key enzymes of cysteine biosynthesis, serine acetyltransferase (SAT) and O-acetylserine(thiol)lyase (OAS-TL), reversibly interact to form the cysteine synthase complex (CSC), which is a known sensor for sulphur supply in the plastids, the cytosol and the mitochondria. I am keen on understanding the intricate regulation processes of CSC formation and cysteine biosynthesis. For example, the tight control of CSC formation and dissociation gives rise to the question whether other factors also trigger CSC formation or destabilize the complex. Recent data also suggest a regulatory role of CSC formation capable to form the basis of communication between different cellular compartments of the plant.


- mit freundlicher Unterstützung der Schmeil-Stiftung, Heidelberg -




/var/www/cos/ / Dr. Anna Speiser