Dr. Damien Devos
Dr. Damien Devos
Im Neuenheimer Feld 230
Fon +49 6221 54-6254
Fax +49 6221 54-5639
ed.grebledieh-inu.soc TEA soved.neimad
We have moved.
From October 1st, the group has relocated to the
We study a poorly characterized bacterial gender of the Planctomycetes phylum, Gemmata obscuriglobus. Planctomycetes are major players in the global nitrogen and carbon cycles and are uniquely capable of anaerobic ammonium oxidation (a globally important nitrogen transformation). Within that phylum, the bacteria of the gender Gemmata are particularly interesting due to their complex intracellular membranous organization that is sustained by proteins showing similarity to the eukaryotic equivalent ones and their capability to internalize fully folded proteins in a process reminiscent of eukaryotic endocytosis (Lonhienne et al., PNAS 2010 ).
We use a combination of computational, molecular biology, and electron-microscopy to first, decipher the peculiar biology of the Planctomycetes and second, to understand their contribution to eukaryotic origin. Computationally, we use structure to push the limits of sequence homology detection. Amongst other tools, we use protein architecture correlation to detect potential relationship between distantly related proteins (Santarella-Mellwig et al. PLoS Biol. 2010 ).
We recently reconstructed G. obscuriglobus in 3D Santarella-Mellwig et al., PLoS Biol. 2013 ).
More details in our DGZ 2012 publication .
We also organized the first meeting dedicated to the PVC bacteria that was a huge success.
Our blog: Microbiology's Platypus
For the past years since 2010, I have given a guest lecturer on "Eukaryotic origin" as part of the course on "Evolution" at the Namur University Belgium.
Since 2012, I am teaching a class of “Programmation simple appliquée à la biologie” (SBIO M211 – 15 h, 2e master en biochimie et biologie moléculaire et cellulaire) at the University of Namur, Belgium. I am thus "maître de conférences".
Since 2013, I am teaching the Grundkurs in Bioinformatik at Heidelberg University for the second year biological students.
Fernando Gutiérrez Espinosa (from the Melo lab , Santiago, Chile), PhD student
Ibai Irastorza, Master student
Juan Carlos Gonzales, Master student