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ed.grebledieh-inu.soc TEA knif.naibaf
Many open questions regarding the integration of V-ATPases into organisms and their environments are still to be addressed. Personally, I am interested in solving some parts of this vast puzzle: By now we know that V-ATPases can carry special modifications and interact with other proteins at certain time points. To describe and characterize that, I am predominantly contributing with proteomics, mostly by subcellular fractionation and protein purification. Amongst others I therefore use a Beckman Coulter Optima XPN-80 Ultracentifuge which is operated by our group.
Viotti C., Krüger F., Krebs M., Neubert C., Fink F., Lupanga U., Scheuring D., Boutté Y., Frescatada-Rosa M., Wolfenstetter S., Sauer N., Hillmer S., Grebe M., Schumacher K. (2013). The Endoplasmic Reticulum Is the Main Membrane Source for Biogenesis of the Lytic Vacuole in Arabidopsis. Plant Cell. 25(9):3434-49.