Ruprecht-Karls-Universität Heidelberg
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Tierphysiologie / Entwicklungsbiologie

Dr. Thomas Thumberger

Dr. Thomas Thumberger
Dr. Thomas Thumberger
Im Neuenheimer Feld 230
69120 Heidelberg
Fon +49 6221 54-6254
Fax +49 6221 54-5639
ed.grebledieh-inu.soc TEA regrebmuht.samoht

 
CCTop - CRISPR/Cas9 target online predictor  Gesellschaft für Entwicklungsbiologie   
     
researcherID profile ResearchGate profile

 


Publikationsliste:

Cilia are required for asymmetric nodal induction in the sea urchin embryo 
Tisler, T., Wetzel, F., Mantino, S., Kremnyov, S., Thumberger, T., Schweickert, A., Blum, M., Vick, P. (2016).
BMC Developmental Biology 16 (1), 28

Considerations for a European animal welfare standard to evaluate adverse phenotypes in teleost fish 
Bert B., Chmielewska J., Bergmann S., Busch M., Driever W., Finger-Baier K., Hößler J., Köhler A., Leich N., Misgeld T., Nöldner T., Reiher A., Schartl M., Seebach-Sproedt A., Thumberger T., Schönfelder G., Grune B. (2016). The EMBO journal 35 (11), 1151-1154
 

An eye on light-sheet microscopy 
Kromm, D., Thumberger, T., and Wittbrodt, J. (2016). Methods in cell biology 133, 105-123
 

Noninvasive In Toto Imaging of the Thymus Reveals Heterogeneous Migratory Behavior of Developing T Cells 
Bajoghli, B., Kuri, P., Inoue, D., Aghaallaei, N., Hanelt, M., Thumberger, T., Rauzi, M., Wittbrodt, J., and Leptin, M. (2015).  J. Immunol.

 

CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool 
Stemmer, M.*, Thumberger, T.*, del Sol Keyer, M., Wittbrodt, J., and Mateo, J.L. (2015). PLoS ONE 10, e0124633.
* = authors contributed equally


The evolution and conservation of left-right patterning mechanisms 
Blum, M., Feistel, K., Thumberger, T., and Schweickert, A. (2014). Development 141, 1603–1613.


A novel serotonin-secreting cell type regulates ciliary motility in the mucociliary epidermis of Xenopus tadpoles 
Walentek, P., Bogusch, S., Thumberger, T., Vick, P., Dubaissi, E., Beyer, T., Blum, M., Schweickert, A.
Development 03/2014; 141(7). doi:10.1242/dev.102343


Ciliogenesis and cerebrospinal fluid flow in the developing Xenopus brain are regulated by foxj1 
Hagenlocher, C., Walentek, P., ller, C.M., Thumberger, T., and Feistel, K. (2013). Cilia 2013, 2:12.


Quantitative analysis of embryogenesis: a perspective for light sheet microscopy 
Höckendorf, B., Thumberger, T., Wittbrodt, J. (2012). Dev. Cell 23, 1111–1120.


Ciliary and non-ciliary expression and function of PACRG during vertebrate development 
Thumberger, T., Hagenlocher, C., Tisler, M., Beyer, T., Tietze, N., Schweickert, A., Feistel, K., & Blum, M. (2012). Cilia,1:13. doi:10.1186/2046-2530-1-13


ATP4a Is Required for Wnt-Dependent Foxj1 Expression and Leftward Flow in Xenopus Left-Right Development. 
Walentek, P., Beyer, T., Thumberger, T., Schweickert, A., & Blum, M. (2012). CellReports, 1–12. doi:10.1016/j.celrep.2012.03.005


Connexin26-mediated transfer of laterality cues in Xenopus
Beyer, T., Thumberger, T., Schweickert, A., & Blum, M. (2012). Biology Open. doi:10.1242/bio.2012760


Serotonin Signaling Is Required for Wnt-Dependent GRP Specification and Leftward Flow in Xenopus
Beyer, T.*, Danilchik, M.*, Thumberger, T.*, Vick, P.*, Tisler, M., Schneider, I., Bogusch, S., et al. (2012). Current Biology, 22(1), 33–39. doi:10.1016/j.cub.2011.11.027
* = authors contributed equally (alphabetical order)


Linking early determinants and cilia-driven leftward flow in left-right axis specification of Xenopus laevis: A theoretical approach. 
Schweickert, A., Walentek, P., Thumberger, T., & Danilchik, M. (2011). Differentiation; research in biological diversity. doi:10.1016/j.diff.2011.11.005


The nodal inhibitor Coco is a critical target of leftward flow in Xenopus
Schweickert, A., Vick, P., Getwan, M., Weber, T., Schneider, I., Eberhardt, M., Beyer, T., et al. (2010). Current biology : CB, 20(8), 738–743. doi:10.1016/j.cub.2010.02.061


Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow.  
Maisonneuve, C., Guilleret, I., Vick, P., Weber, T., Andre, P., Beyer, T., Blum, M., et al. (2009). Development (Cambridge, England), 136(17), 3019–3030. doi:10.1242/dev.038174


Flow on the right side of the gastrocoel roof plate is dispensable for symmetry breakage in the frog Xenopus laevis Vick, P., Schweickert, A., Weber, T., Eberhardt, M., Mencl, S., Shcherbakov, D., Beyer, T., et al. (2009). Developmental biology, 331(2), 281–291. doi:10.1016/j.ydbio.2009.05.547


Evolution of leftward flow. 
Blum, M., Weber, T., Beyer, T., & Vick, P. (2009). Seminars in Cell & Developmental Biology, 20(4), 464–471. doi:10.1016/j.semcdb.2008.11.005


Xenopus, an ideal model system to study vertebrate left-right asymmetry. 
Blum, M., Beyer, T., Weber, T., Vick, P., Andre, P., Bitzer, E., & Schweickert, A. (2009). Developmental dynamics : an official publication of the American Association of Anatomists, 238(6), 1215–1225. doi:10.1002/dvdy.21855


Cilia-driven leftward flow determines laterality in Xenopus
Schweickert, A., Weber, T., Beyer, T., Vick, P., Bogusch, S., Feistel, K., & Blum, M. (2007). Current biology : CB, 17(1), 60–66. doi:10.1016/j.cub.2006.10.067


/var/www/cos/ / http://www.cos.uni-heidelberg.de/ Dr. Thomas Thumberger