Ruprecht-Karls-Universität Heidelberg
Welcome to COS Heidelberg

The Centre for Organismal Studies (COS) Heidelberg aims to study organismic biology beyond the borders of organisational level. Research and teaching at COS is dedicated to study organismic biology from the basic molecular principles to cell biology, developmental biology and physiology both in plants and in animals and to further extend into evolution, biodiversity, systems biology and biotechnology.



Bertalanffy Lecture

Ottoline Leyser (Sainsbury Laboratory, University of Cambridge) will be the speaker of the ninth Bertalanffy Lecture on April 28/29, 2016.


Visiting Professorship for Marcus Koch

Marcus Koch was appointed a permanent visiting professor at the Charles University in Prague.

Upcoming Event:

COS PhD/Postdoc Seminar

Reports on current research

COS PHD students and PostDocs

COS Heidelberg

31st of May 2016 01:15 PM

INF 230, R. 00.005

Recent Publications:
Arendt, D.; Tosches, M.A.; Marlow, H. 2015 From nerve net to nerve ring, nerve cord and brain - evolution of the nervous system Nat Rev Neurosci 17 1 61-72 doi: 10.1038/nrn.2015.15 [Link]
Koch, M.A. 2015 A new chromosome was born: comparative chromosome painting in Boechera Trends Plant Sci doi: 10.1016/j.tplants.2015.07.001 [Link]
Jouannet, V.; Brackmann, K.; Greb, T. 2015 (Pro)cambium formation and proliferation: two sides of the same coin? Curr Opin Plant Biol 23 54-60 doi: 10.1016/j.pbi.2014.10.010 [Link]
Schuster, C.; Gaillochet, C.; Lohmann, J.U. 2015 Arabidopsis HECATE genes function in phytohormone control during gynoecium development Development 142 19 3343-3350 doi: 10.1242/dev.120444 [Link]
Brunet, T.; Arendt, D. 2016 From damage response to action potentials: early evolution of neural and contractile modules in stem eukaryotes Philos Trans R Soc Lond B Biol Sci 371 1685 doi: 10.1098/rstb.2015.0043 [Link]
Caroti, F.; Urbansky, S.; Wosch, M.; Lemke, S. 2015 Germ line transformation and in vivo labeling of nuclei in Diptera: report on Megaselia abdita (Phoridae) and Chironomus riparius (Chironomidae) Dev Genes Evol 225 3 179-186 doi: 10.1007/s00427-015-0504-5 [Link]
Grawunder, D.; Hambleton, E.A.; Bucher, M.; Wolfowicz, I.; Bechtoldt, N.; Guse, A. 2015 Induction of Gametogenesis in the Cnidarian Endosymbiosis Model Aiptasia sp Sci Rep 5 15677 doi: 10.1038/srep15677 [Link]
Dietz, K.-J.; Hell, R. 2015 Thiol switches in redox regulation of chloroplasts: balancing redox state, metabolism and oxidative stress Biol Chem 396 5 483-494 doi: 10.1515/hsz-2014-0281 [Link]
Su, T.; Wolf, S.; Han, M.; Zhao, H.; Wei, H.; Greiner, S.; Rausch, T. 2016 Reassessment of an Arabidopsis cell wall invertase inhibitor AtCIF1 reveals its role in seed germination and early seedling growth Plant Mol Biol 90 1-2 137-155 doi: 10.1007/s11103-015-0402-2 [Link]
Willems, P.H.G.M.; Pahle, J.; Stalpers, X.L.; Mugahid, D.; Nikolaew, A.; Koopman, W.J.H.; Kummer, U. 2015 PKC-mediated inhibitory feedback of the cholecystokinin 1 receptor controls the shape of oscillatory Ca(2)(+) signals Febs J 282 11 2187-2201 doi: 10.1111/febs.13267 [Link]
Forner, J.; Pfeiffer, A.; Langenecker, T.; Manavella, P.A.; Lohmann, J.U. 2015 Germline-transmitted genome editing in Arabidopsis thaliana Using TAL-effector-nucleases PLoS One 10 3 e0121056 doi: 10.1371/journal.pone.0121056 [Link]
Birke, H.; De Kok, L.J.; Wirtz, M.; Hell, R. 2015 The role of compartment-specific cysteine synthesis for sulfur homeostasis during H2S exposure in Arabidopsis Plant Cell Physiol 56 2 358-367 doi: 10.1093/pcp/pcu166 [Link]
Friedrich, J.; Sorge, S.; Bujupi, F.; Eichenlaub, M.P.; Schulz, N.G.; Wittbrodt, J.; Lohmann, I. 2016 Hox Function Is Required for the Development and Maintenance of the Drosophila Feeding Motor Unit Cell Rep 14 4 850-860 doi: 10.1016/j.celrep.2015.12.077 [Link]
Kriegel, A.; Andres, Z.; Medzihradszky, A.; Kruger, F.; Scholl, S.; Delang, S.; Patir-Nebioglu, M.G.; Gute, G.; Yang, H.; Murphy, A.S.; Peer, W.A.; Pfeiffer, A.; Krebs, M.; Lohmann, J.U.; Schumacher, K. 2015 Job Sharing in the Endomembrane System: Vacuolar Acidification Requires the Combined Activity of V-ATPase and V-PPase Plant Cell 27 12 3383-3396 doi: 10.1105/tpc.15.00733 [Link]
Petersen, H.O.; Hoger, S.K.; Looso, M.; Lengfeld, T.; Kuhn, A.; Warnken, U.; Nishimiya-Fujisawa, C.; Schnolzer, M.; Kruger, M.; Ozbek, S.; Simakov, O.; Holstein, T.W. 2015 A Comprehensive Transcriptomic and Proteomic Analysis of Hydra Head Regeneration Mol Biol Evol 32 8 1928-1947 doi: 10.1093/molbev/msv079 [Link]
Lopez, L.; Barreiro, R.; Fischer, M.; Koch, M.A. 2015 Mining microsatellite markers from public expressed sequence tags databases for the study of threatened plants BMC Genomics 16 781 doi: 10.1186/s12864-015-2031-1 [Link]

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