Ruprecht-Karls-Universität Heidelberg
Welcome to COS Heidelberg

The Centre for Organismal Studies (COS) Heidelberg aims to study organismic biology beyond the borders of organisational level. Research and teaching at COS is dedicated to study organismic biology from the basic molecular principles to cell biology, developmental biology and physiology both in plants and in animals and to further extend into evolution, biodiversity, systems biology and biotechnology.

News:

 

New Collaborative Research Centre

The new Collaborative Research Centre “Mechanisms and Function of Wnt signaling” lead by Thomas Holstein will receive a four year funding grant by the DFG.

 

 

New Research Units

The Research Units „The concert of Dolichol-based Glycosylation: from Molecules to Disease Models“ headed by Sabine Strahl and „Morphodynamics of Plants“ headed by Alexis Maizel will each receive a three year funding grant by the DFG.

Recent Publications:
Neubert, P.; Strahl, S. 2016 Protein O-mannosylation in the early secretory pathway Curr Opin Cell Biol 41 100-108 doi: 10.1016/j.ceb.2016.04.010 [Link]
Neubert, P.; Halim, A.; Zauser, M.; Essig, A.; Joshi, H.J.; Zatorska, E.; Larsen, I.S.B.; Loibl, M.; Castells-Ballester, J.; Aebi, M.; Clausen, H.; Strahl, S. 2016 Mapping the O-Mannose Glycoproteome in Saccharomyces cerevisiae Mol Cell Proteomics 15 4 1323-1337 doi: 10.1074/mcp.M115.057505 [Link]
Meitinger, F.; Pereira, G. 2016 Visualization of Cytokinesis Events in Budding Yeast by Transmission Electron Microscopy Methods Mol Biol 1369 87-95 doi: 10.1007/978-1-4939-3145-3_7 [Link]
Wei, H.; Bausewein, A.; Steininger, H.; Su, T.; Zhao, H.; Harms, K.; Greiner, S.; Rausch, T. 2016 Linking Expression of Fructan Active Enzymes, Cell Wall Invertases and Sucrose Transporters with Fructan Profiles in Growing Taproot of Chicory (Cichorium intybus): Impact of Hormonal and Environmental Cues Front Plant Sci 7 1806 doi: 10.3389/fpls.2016.01806 [Link]
Wei, H.; Bausewein, A.; Greiner, S.; Dauchot, N.; Harms, K.; Rausch, T. 2017 CiMYB17, a stress-induced chicory R2R3-MYB transcription factor, activates promoters of genes involved in fructan synthesis and degradation New Phytol 215 1 281-298 doi: 10.1111/nph.14563 [Link]
Bausewein, D.; Engel, J.; Jank, T.; Schoedl, M.; Strahl, S. 2016 Functional similarities between the protein O-mannosyltransferases Pmt4 from baker's yeast and human POMT1 J Biol Chem doi: 10.1074/jbc.M116.739128 [Link]
Gryaznova, Y.; Koca Caydasi, A.; Malengo, G.; Sourjik, V.; Pereira, G. 2016 A FRET-based study reveals site-specific regulation of spindle position checkpoint proteins at yeast centrosomes Elife 5 doi: 10.7554/eLife.14029 [Link]


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