Ruprecht-Karls-Universität Heidelberg
Welcome to COS Heidelberg

The Centre for Organismal Studies (COS) Heidelberg aims to study organismic biology beyond the borders of organisational level. Research and teaching at COS is dedicated to study organismic biology from the basic molecular principles to cell biology, developmental biology and physiology both in plants and in animals and to further extend into evolution, biodiversity, systems biology and biotechnology.



Margarete von Wrangell-Programme

Anne Pfeiffer was awarded support by the Margarete von Wrangell programme of the state Baden-Württemberg.


Visiting Professorship for Marcus Koch

Marcus Koch was appointed a permanent visiting professor at the Charles University in Prague.

Upcoming Event:

COS PhD/Postdoc Seminar

Reports on current research

COS PHD students and PostDocs

COS Heidelberg

4th of October 2016 01:15 PM

INF 230, R. 00.005

Recent Publications:
Gaillochet, C.; Lohmann, J.U. 2015 The never-ending story: from pluripotency to plant developmental plasticity Development 142 13 2237-2249 doi: 10.1242/dev.117614 [Link]
Muir, G.; Ruiz-Duarte, P.; Hohmann, N.; Mable, B.K.; Novikova, P.; Schmickl, R.; Guggisberg, A.; Koch, M.A. 2015 Exogenous selection rather than cytonuclear incompatibilities shapes asymmetrical fitness of reciprocal Arabidopsis hybrids Ecol Evol 5 8 1734-1745 doi: 10.1002/ece3.1474 [Link]
Hohmann, N.; Wolf, E.M.; Lysak, M.A.; Koch, M.A. 2015 A Time-Calibrated Road Map of Brassicaceae Species Radiation and Evolutionary History Plant Cell 27 10 2770-2784 doi: 10.1105/tpc.15.00482 [Link]
Bausewein, D.; Engel, J.; Jank, T.; Schoedl, M.; Strahl, S. 2016 Functional similarities between the protein O-mannosyltransferases Pmt4 from baker's yeast and human POMT1 J Biol Chem doi: 10.1074/jbc.M116.739128 [Link]
Forner, J.; Pfeiffer, A.; Langenecker, T.; Manavella, P.A.; Lohmann, J.U. 2015 Germline-transmitted genome editing in Arabidopsis thaliana Using TAL-effector-nucleases PLoS One 10 3 e0121056 doi: 10.1371/journal.pone.0121056 [Link]
Papagiannouli, F.; Lohmann, I. 2015 Stage-specific control of stem cell niche architecture in the Drosophila testis by the posterior Hox gene Abd-B Comput Struct Biotechnol J 13 122-130 doi: 10.1016/j.csbj.2015.01.001 [Link]
Lust, K.; Wittbrodt, J. 2015 Hold your breath Elife 4 doi: 10.7554/eLife.12523 [Link]
Friedrich, J.; Sorge, S.; Bujupi, F.; Eichenlaub, M.P.; Schulz, N.G.; Wittbrodt, J.; Lohmann, I. 2016 Hox Function Is Required for the Development and Maintenance of the Drosophila Feeding Motor Unit Cell Rep 14 4 850-860 doi: 10.1016/j.celrep.2015.12.077 [Link]
Birke, H.; Hildebrandt, T.M.; Wirtz, M.; Hell, R. 2015 Sulfide detoxification in plant mitochondria Methods Enzymol 555 271-286 doi: 10.1016/bs.mie.2014.11.027 [Link]
Neubert, P.; Strahl, S. 2016 Protein O-mannosylation in the early secretory pathway Curr Opin Cell Biol 41 100-108 doi: 10.1016/ [Link]
Reinhardt, R.; Centanin, L.; Tavhelidse, T.; Inoue, D.; Wittbrodt, B.; Concordet, J.-P.; Martinez-Morales, J.R.; Wittbrodt, J. 2015 Sox2, Tlx, Gli3, and Her9 converge on Rx2 to define retinal stem cells in vivo Embo J 34 11 1572-1588 doi: 10.15252/embj.201490706 [Link]
Robinson, D.G.; Neuhaus, J.-M. 2016 Receptor-mediated sorting of soluble vacuolar proteins: myths, facts, and a new model J Exp Bot doi: 10.1093/jxb/erw222 [Link]
Lopez, L.; Barreiro, R.; Fischer, M.; Koch, M.A. 2015 Mining microsatellite markers from public expressed sequence tags databases for the study of threatened plants BMC Genomics 16 781 doi: 10.1186/s12864-015-2031-1 [Link]
Gryaznova, Y.; Koca Caydasi, A.; Malengo, G.; Sourjik, V.; Pereira, G. 2016 A FRET-based study reveals site-specific regulation of spindle position checkpoint proteins at yeast centrosomes Elife 5 doi: 10.7554/eLife.14029 [Link]
Ramanathan, N.; Simakov, O.; Merten, C.A.; Arendt, D. 2015 Quantifying Preferences and Responsiveness of Marine Zooplankton to Changing Environmental Conditions using Microfluidics PLoS One 10 10 e0140553 doi: 10.1371/journal.pone.0140553 [Link]
Arendt, D.; Tosches, M.A.; Marlow, H. 2015 From nerve net to nerve ring, nerve cord and brain - evolution of the nervous system Nat Rev Neurosci 17 1 61-72 doi: 10.1038/nrn.2015.15 [Link]
Meitinger, F.; Pereira, G. 2016 Visualization of Cytokinesis Events in Budding Yeast by Transmission Electron Microscopy Methods Mol Biol 1369 87-95 doi: 10.1007/978-1-4939-3145-3_7 [Link]
Veith, N.; Solheim, M.; van Grinsven, K.W.A.; Olivier, B.G.; Levering, J.; Grosseholz, R.; Hugenholtz, J.; Holo, H.; Nes, I.; Teusink, B.; Kummer, U. 2015 Using a genome-scale metabolic model of Enterococcus faecalis V583 to assess amino acid uptake and its impact on central metabolism Appl Environ Microbiol 81 5 1622-1633 doi: 10.1128/AEM.03279-14 [Link]
Pfeiffer, A.; Janocha, D.; Dong, Y.; Medzihradszky, A.; Schone, S.; Daum, G.; Suzaki, T.; Forner, J.; Langenecker, T.; Rempel, E.; Schmid, M.; Wirtz, M.; Hell, R.; Lohmann, J.U. 2016 Integration of light and metabolic signals for stem cell activation at the shoot apical meristem Elife 5 doi: 10.7554/eLife.17023 [Link]

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