Dr. Jan Felix Evers
 | Dr. Jan Felix Evers
Im Neuenheimer Feld 230 69120 Heidelberg Fon +49 6221 54-6469 jan-felix.evers AET cos.uni-heidelberg.de |
Coordinated behaviour is the result of successful neuronal network assembly. During embryogenesis, excitability and connectivity of neurons must be carefully adjusted so that functional networks can arise. We investigate how individual neurons select from the vast number of potential partner neurons and form synapses with only a few in the inherently variable environment of the central nervous system.
Using the locomotor system of Drosophila melanogaster, we develop and apply a number of cutting edge techniques to uncover the molecular mechanisms that regulate developmental plasticity and functional homeostatsis:
- live 3-dimensional imaging of dynamic growth and synaptogenesis of individual pairs of neurons;
- 3-dimensional computational analysis of neuronal structure and interaction with synaptic partners;
- optogenetically inducible labeling of endogenous synaptic proteins in individual cells with a conditional marker.
Open Positions
We are currently looking for a motivated PhD student interested in the molecular mechanisms that regulate synaptic physiology. For details please check the hbigs job positings.
Please contact Jan Felix Evers for inquiries for open positions in the lab.
We have openings for master projects and lab rotations.