Ruprecht-Karls-Universität Heidelberg
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Plant Molecular Physiology

Dr. Janine Höll

Dr. Janine Höll
Dr. Janine Höll
janine.hoell AET

Regulation of Stilbene Synthesis in Vitis vinifera and the influence of Flavonoid modification on its function

Stilbenes are a small family of plant secondary metabolites and like flavonoids derived from the phenylpropanoid pathway.

The synthesis of these phenolic componds is catalysed by the initial enzymes stilbene synthase (STS) and chalcone synthase (CHS) by using the same substrates.

The increasing knowledge about the biological function and the health-promoting effects of fruit-derived flavonoids and stilbenes leds to an enhanced interest in the elucidation of biosynthetic pathways involved in their biosynthesis and modification. Recently, transcription factors controlling different pathway branches of the flavonoid pathway have been elucidated but a factor controlling stilbene biosynthesis has not been identified yet. Furthermore, the vast majority of the genes responsible for flavonoid and stilbene diversity, which has been shown to influence bioavailability, antioxidant capacity and stability of the resulting polyphenol, are yet completely unknown. Therefore we are interested in the identification and characterisation of the regulators of STS synthesis and genes encoding enzymes modifying flavonoids and stilbenes.



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