Stammzellbiologie
SFB 873
Maintenance and Differentiation of Stem Cells
in Development and Disease
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Research in Progress and Seminar Series
The SFB873 organizes two alternating series of monthly seminars for internal progress report (Research in Progress) and high-profile external speakers (Seminar Series) , respectively.
They are held every other Friday at noon, followed by a common lunch, to facilitate exchange of ideas and informal interactions among members of the SFB and the Heidelberg life-science community.
| Research in Progress | Seminar Series |
|---|---|
| 2015 | 2015 |
| 2014 | 2014 |
| 2013 | 2013 |
| 2012 | 2012 |
| 2011 | 2011 |
Research in Progress
12:00-13:00 Seminar Room ZMBH
2015
| 09 JAN |
Thomas Stiehl (B08) "Feedback Signal Myelodysplastic Syndromes - Insights from Mathematical Modeling" Georgis Kalamakis (B09) "The aging subventricular zone" |
| 06 FEB |
Cornelia Monzel (B07) "Molecular Cues controlling Hematopoietic Stem Cell Adhesion and Migration in Model Bone Marrow Niche" Georgis Kalamakis (B09) "The aging subventricular zone" Methods: Stephan Kirchmaier (A03) "(Sub)cloning, Methods+Tricks" |
| 06 MAR |
Juan Luis Mateo Cerdan (A03) "Characterisation of the neural stem cell gene regulatory network" Marc Thier (B04) "Rolling the Dice for pluripotency: Implication of small non-coding RNAs for iPSC induction" Methods: Daniel Klimmeck (B04) "Proteome" |
| 17 APR |
Beate Scholz (B06) "Endothelial RSPO3 controls vascular stability and pruning through non canonical WNT/Ca2+/NFAT signaling/quot; Jinyi Xiang (A02) "Regulation of String during Drosophila intestinal stem cell proliferation" Methods: Michael Gebert (B01) "INTACT" |
| 08 MAY |
Anne Pfeiffer (B01) "The Arabidopsis TOR Kinase, an Integrator of Light Derived Signals that Controls Plant Stem Cell Activation" Jun Zhou (A06) "ATF3 acts as a rheostat to control JNK signaling in intestinal regeneration and inflammation" Methods: Mahak Singhal (B06) and Andrej Miotk (B01) "RNA-seq" |
| 12 JUN |
Sergio Acebron (B03) and Katrin Busch (B11) Methods: Daniel Klimmeck (B04) "Electron Microscopy" |
| 10 JUL |
Isabel Krämer (A11) and (B09) Methods: Nina Cabezas (B04) and Enric Llorens (B09) |
| 07 AUG |
Fani Papagiannouli (B02) and (A14) Methods: Mahak Singhal (B09) and Lisa Paleske (B04) "FACS" |
| 18 SEP |
(B07) and Leila Martins (A12) Methods: Maria de Sol (A11) "CRISPR / CAS" |
| 02 OCT |
(A01) and Borhan Saeed (A13) Methods: Andrej Miotk (B01), Nina Cabezas (B04) and Daniel Klimmeck (B04) "Data Mining" |
| 13 NOV |
(B04) and (B06) Methods: Peer Wünsche (A12) "Lineage analysis 'barcoding'" |
| 04 DEC |
(A02) and (B01) Methods: Florian Heigwer (A06) "CRISPR / CAS web tool" |
2014
| 10 JAN |
Shayda Hemmati (A07) "Identification of Key Regulations of Post-embryonic Hematopoiesis" Beate Scholz (B06) "The role of Wnt signaling in the regulation of blood vessel remodeling" |
| 07 FEB |
Simon Raffel (B04) "Protoemic and Transcriptomic Profiling of Acute Myeloid Leukemia Stem Cells" Katharina Nöske (B10)"Asymmetic cell division in human epidermis" |
| 07 MAR |
Fani Papagiannouli (B02) "Hox genes as micromanagers of the Drosphilia male stem cell niche" Cristina Sirrenberg- Cruciat (B03) "Regulation of Casein kinase 1 by Wnt/beta-catenin signaling" |
| 04 APR |
Robert Reinhard (A03) "Transkriptional control of stemness in the retina" Thomas Stiehl (B08) "Impact of Leukemic Stem Cell Properties on Clinical Course and Patient Prognosis - Insights from Mathematical Modeling" |
| 09 MAY |
Iris Augustin (A06) "Mouse embryonic stem cell need Wnts for survival and lieage differentiation" Enric Llorens Bobadilla (B09) "Injury-induced fate plasticity in neural stem cells" |
| 06 JUN |
Marta Galach (A08) "Efficient generation of early epithelial cells from hiPSCs" Gabor Daum (B01) "Cell-to-cell movement of a stem cell inducing transcription factor in plants" |
| 04 JUL |
Oleg Simakov (A01) "Genomic signatures and stem cells in hydra regeneration" Simon Haas (B05) "Inflammation-driven fast-track differentiation of HSCs into the megakaryocytic lineage" |
| 01 AUG |
Yinhua Jin (A02) "EGFR / RAS / MAPK Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua and its target, Pointed" Alexandra Burk & Van Hoang (B07) "Quantifying Adhesion Mechanisms of Human Hematopoietic Stem and Progenitor Cell on In Vitro Bone Marrow Niche Models" |
| 05 SEP |
Susanne Bartels (B06) "Angiopoietin-2 as therapeutic target for GvHD" Nina Cabezas (B04) "Identification of Regulatory Networks in HSCs and their Immediate Progeny Via Integrated Proteome, Transcriptome and DNA Methylome Analysis" |
| 10 OCT |
Fani Papagiannouli (B02) "Stage-specific control of niche architecture in the Drosophila testis by the posterior Hox gene Abd-B" Arturo Gutierrez (A03) "Vertebrate retinal stem cells: Towards dissecting the genetic network mediated by Rx2 in Medaka" |
| 07 NOV |
Sergio P. Acebron (B03) "WNT-dependent stabilization of proteins (WNT/STOP) in mitosis promotes growth and cell cycle progression" Fabian Graf (A06) "Mesenchymal stem cells mediate prostate cancer cell migration via diffusible extracellular matrix proteins" |
| 05 DEC |
Christian Wenzl (B01) "Using 3D-microscopy to study environmental impact on stem cell homeostasis in plants" Frederik Ziebell (B08) "Mathematical Modelling of Neural Stem Cell Dynamics in the Adult Hippocampus" |
2013
| 11 JAN |
Devanjali Dutta (A02) "Transcriptome profiling of Drosophila intestinal cell populations by RNA Sequencing" Susanne Bartels (B06) "Angiopoietin-2 is a facilitator of hematopoietic stem and progenitor mobilization" |
| 01 FEB |
Matthias Bernhardt (A08) "Reprogramming of human melanoma cells towards induced pluripotency" Damian Wollny (B09) "Homeostasis and Cancer Initiation in the Adult Pancreas" |
| 01 MAR |
Melania Tesio (B04) "The deubiquitinase CYLD controls hematopoietic stem cells dormancy via the NEMO kinase" Cristina Sirrenberg-Cruciat (B03) "RNA Helicase DDX3 is a Regulatory Subunit of Casein Kinase 1 in Wnt/beta-catenin Signaling" |
| 05 APR |
Burkhard Höckendorf (A03) "A quantitative clonal analysis of the growing fish retina" Frederik Ziebell (B08) "Mathematical modelling of adult neurogenesis" |
| 03 MAY |
Fabian Graf (A06) "Mesenchymal stromal cells: Possible mediators of bone metastasis?" Julieta Maldera (A02) "Identifying factors required for Drosophila intestinal stem cell response to tissue damage" |
| 07 JUN |
Fani Papagiannouli (B2) "Hox genes as micromanagers of the Drosophila male stem cell niche" Judith Schlupf (A09) "Expression anf function of the IGF family during extra-embryonic endoderm differentiation" |
| 05 JUL |
Lionel Larribere (A08) "Human iPSCs-based model of Neurofibromatosis type I" Daniel Espadinha (B5) "Targeting quiescent leukemic stem cells through a combined treatment strategy" |
| 02 AUG |
Sergio Perez Acebron (B03) "Wnt-mediated stabilization of mitotic proteins regulates cell growth and proliferation" Robert Hermann (B09) "Regulation of Neural Progenitor Proliferation by Ankhd1" |
| 06 SEP |
Aine Prendergast (B05) "The stress response of the hematopoietic stemm cell niche" Felix Oppel (A07) "Clonal Dynamics and Phenotypic Plasticity within the Pancreatic Tumor-Initiating Cell Compartment" |
| 11 OCT |
Philipp Scholz (B10) "Stem Cells in Skin Wound Healing" Lisa Dohrn (B04) "Defining a Long-Range Enhancer that regulates c-Myc in Hematopoietic Stem Cells" |
| 08 NOV |
Joachim Forner (B01) "Counting the Number of Stem Cells in the Shoot Apical Meristem of Arabidopsis thaliana" Monika Petersson (A02) "Delineating steps of tumor progression of intestinal stem cell-derived precursors in the adult fly" |
| 06 DEC |
Hendrik Petersen (A01) "Head regeneration in Hydra: A Quantitative Proteomic and Phosphoproteomic Approach" WenWen Wang (B07) "Clonal Heterogeneity in Leukemic and 'Pre-leukemic' in Stem Cells" |
2012
| 13 JAN |
Stefanie Thamm (B05) "LPS induced activation of hematopoietic stem cells" Rainer Saffrich (B07) "MSC 3D culture systems as model of the hematopoietic stem cell niche" |
| 03 FEB | Enric Llorens (B09) "Induction of alternative fate choices in adult NSCs" |
| 02 MAR | Robert Reinhard (A03) "Deciphering the retinal stem cell-specific gene regulatory network in O.latipes" |
| 30 MAR |
Shayda Hemmati (A07) "Control of Stem Cell Fate by Key Regulators of Post-embryonic Hematopoiesis" Thomas Stiehl (B08) "Can Mathematical Models Help to Understand Qualitative Behaviour of Leukemia Initiating Cells?" |
| 04 MAY |
Hind Medyouf (B04) "Chracterization of malignant hematopoietic stem cells from patients with myelodysplastic syndrome (MDS) in a xenograft model" Joachim Forner (B01) "Counting the Number of Stem Cells in Shoot Apical Meristem of Arabidopsis thaliana" |
| 01 JUN |
Michael Suchanek (A06) "Screening in primary human mesenchymal stem cells" Lionel Larribere (A08) "Diffentiation of human iPS cells into melancytes" |
| 06 JUL |
Armin Ehninger (B04) "The role of SPARC and Tenascin C in HSC seeding, engraftment and hemotopoietic regeneration" Jerome Korzelius (A02) "Studying the dynamics of Rbf/dE2F transcriptional regulation in the Drosophila midgut by tissue-specific ChIP-Seq" |
| 03 AUG |
Elisa Specker (B10) "The Epidermal Stem Cell - A new approach to identify stem cells a viable label-retaining cells" Eva-Maria Hartinger (A07) "Proliferative and Cell Cycle Activity of Transplantable Colon Cancer Initiaating Cells" |
| 07 SEP |
Moritz Drachsler (B09) "The role of CD95 in Glioblastoma initiation" Hanna Uckelmann (B05) "The role of Sca-1 in IFNalpha induced activation of HSCs" |
| 05 OCT | Iris Augustin (A06) and Anna Medzihradzky (B01) |
| 09 NOV |
Katrin Schrenk-Siemens (B07) "hES cell-derived neural crest cells: a tool to study epithelial-mesenchymal transition (EMT)" Larissa Carnevalli (B04) "Role of Granzyme B in hematpoietic stem cell homeostasis and activation" |
| 07 DEC |
Isabel Hofmann (B07) "Shear stress regulates adhesion and rolling of CD44+ leikemic and hematopoietic progenitor cells on hyluronic acid" Leonard Nevaril (B10) "The role of stroma for long-term epidermal regeneration" |
2011
| 04 FEB | Patrick Wuchter (B07) and Zhong Zao (B01) and Alexander Kohlmaier (A02) |
| 04 MAR | Stephan Wurzer (B05) and Desiree Glagow (B09) and Susanne Bartels (B06) |
| 01 APR | Fani Papagianoulli (B02) and Thomas Stiehl (B08) and Berit Falkowska-Hansen (B10) |
| 06 MAY | Daniel Nowak (A08) and Eike Buss (B07) and Lazaro Centanin (A03) |
| 03 JUN | Judith Schlupf (A09) and Gerit Erdmann (A06) and Robert Hermann (B09) |
| 01 JUL | Christopher Hoffmann (A07) and Melania Tesio (B04) and Andrey Glinka (B03) |
| 05 AUG | Daniel Klimmeck (B04) and Friederike Herbst (A07) and Parthive Patel (A02) |
| 07 OCT | Roberta Scognamiglio (B04) and Claudia Korn (B06) |
| 04 NOV | Jinyi Xiang (A02) and Ines Brückmann (B04) and Christian Volz (A06) |
| 02 DEC | Marta Galach (A08) and Thomas Kaindl (B07) and Andrej Miotk (B01) |
Seminar Series
12:00-13:30 Seminar Room ZMBH
2015
| 23 JAN |
Thomas Laux Institute of Biology III, University of Freiburg, Freiburg, Germany "Initiation of the embryo body axis in Arabidopsis thaliana" |
| 20 FEB |
Colette Dehay CNRS (Centre Nacional de la Recherche Scientifique), Department of Embryonic Stem Cell and Cortical Development, Bron Cedex, France "A primate-specific cellular and molecular logic for OSVZ expansion" |
| 20 MAR |
Steven Pollard MRC Centre for Regenerative Medicine The University of Edinburgh, Edinburgh, Great Britain "Programming and reprogramming brain tumour stem cells" |
| 24 APR |
Henrik Kaessmann Center for Integrative Genomics, UNIL, Lausanne, Switzerland "Functional evolution of mammalian genomes" |
| 22 MAY |
Alexander Aulehla EMBL, Heidelberg, Germany |
| 26 JUN |
Heinrich Reichert Biozentrum, University of Basel, Basel, Switzerland |
| 24 JUL |
Veronika Sexl Institute of Pharmacology and Toxicology, Department of Biomedical Sciences, University of Veterinary Medicine of Vienna, Vienna, Austria |
| 25 SEP |
Carien M. Niessen Department of Dermatology and CECAD, University of Cologne, Cologne, Germany |
| 09 OCT |
Carmen Ruiz de Almodóvar Heidelberg University, Biochemistry Center (BZH), Heidelberg, Germany |
| 16 OCT |
Bertie Göttgens Cambridge University Department of Haematology, Cambridge Institute for Medical Research & Wellcome Trust and MRC Stem Cell Institute, Cambridge, UK |
| 20 NOV |
Simón Méndez Ferrer Fundación CNIC Carlos III - Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain |
| 18 DEC |
Michael Wegner Institute of Biochemistry, Erlangen, Germany |
2014
| 24 JAN |
Dirk Strunk Paracelsus Medical University Salzburg, Salzburg, Austria "HuNiche: A novel humanized bone and marrow niche formation mouse model" |
| 21 MAR |
Juan Manuel Encinas Achucarro Basque Center for Neuroscience, Zamudio, Spain "Reactive Neural Stem Cells and Impairment of Neurogenesis in the Adult Hippocampus" |
| 25 APR |
Phil Jones MRC Cancer Unit, University of Cambridge, Cambridge, UK “How oncogenic mutation alters progenitor cell behaviour in squamous carcinogenesis” |
| 23 MAY |
Gian-Paolo Dotto University of Lausanne Epalinges, Lausanne, Switzerland “Multifactorial Notch and ER control of field cancerization and squamous carcinoma development” |
| 27 JUN |
Albrecht Müller, Institut für medizinische Strahlenkunde und Zellforschung im ZEMM, Würzburg, Germany "Getting to the root of Polycomb function in ESCs and HSCs" |
| 19 SEP |
Heinrich Jasper , The Buck Institute for Research on Aging, Novato, CA, USA "Stem cells and aging: lessons from Drosophila" |
| 21 NOV |
András Simon Karolinska Institutet, Stockholm, Sweden "Salamandar regeneration: regulation and evolution" |
2013
| 18 JAN |
Magdalena Götz Helmholtz Zentrum München, Munich, Germany "A new source of Neural Stem Cells After Brain Injury" |
| 15 FEB |
Michael A. Rieger Loewe Center for Cell and Gene Therapy Frankfurt, University Hospital Frankfurt, Frankfurt, Germany "Continous single cell observation of hematopoietic stem cell fate decisions" |
| 15 MAR |
Marcos Vidal The Beatson Institute for Cancer Research, Glasgow, UK “Intestinal Stem Cells in self-renewal, regeneration and tumorigenesis in Drosophila” |
| 19 APR |
Axel Behrens Cancer Research UK ,London, UK “Stem Cell regulation and cancer” |
| 17 MAY |
Dominique Bonnet London Research Institute, London, UK “New heterogeneity of Leukaemic stem cells: implications for therapy” |
| 21 JUN |
Anne-Claude Gavin EMBL, Heidelberg, Germany "Systematic screen reveals new function for a family oxysterol-binding proteins" |
| 20 SEP |
Allsion Bardin BDD - Institut Curie, Paris, France "Controls of tissue specific stem cells: from cell-cell signaling to chromatin remodeling" |
| 18 OCT |
Catherin Niemann CMMC at the University of Cologne, Cologne, Germany "Molecular mechanisms in stem cell-driven skin tumor initiation" |
| 22 NOV |
Cristiona lo Celso Imperial College London, London, UK "In vivo imaging of nomral and malignant hematopoiesis in mouse bone marrow" |
2012
| 20 JAN |
Leanne Jones Salk Institute, San Diego, USA "Mechanisms regulating maintenance of stem cells and the stem cell niche" |
| 17 FEB |
Halyna Shcherbata Max Planck Institute for biophysical Chemistry, Göttingen, Germany "Steroid-induced microRNA let-7 acts as a spatio-temporal code for neuronal cell fate in Drosophila learning centers " |
| 16 MAR |
Owen Sansom The Beatson Institute for Cancer Research, Glasgow, UK "Investigating Wnt signalling, intestinal stem cells and cancer in vivo" |
| 27 APR |
Rüdiger Simon Heinrich Heine University Düsseldorf, Düsseldorf, Germany “Stem cell regulation by peptides and receptors in plants” |
| 25 MAY |
Hartmut Geiger Ulm University, Department of Dermatology and Allergic Diseases, Ulm, Germany “Hematopoietic stem cell rejuvenation, polarity and Cdc42” |
| 15 JUN |
Joachim Wittbrodt Centre for Organismal Studies (COS), Heidelberg, Germany "The retinal stem cell niche and its regulatory features" |
| 20 JUL |
Christoph Lutz Heidelberg University Hospital, Heidelberg, Germany "Phenotypic and Genetic Heterogeneity in Childhood Acute Lymphoblastic Leukaemia" |
| 17 AUG |
Walter Birchmeier Max Delbrück Center for Molecular Medicine, Berlin-Buch, Germany "Wnt/?-catenin signaling in stem and cancer stem cells" |
| 21 SEP |
Axel Behrens London Research Institute, London, UK |
| 19 OCT |
Petri Salven University of Helsinki, Department of Pathology, Helsinki, Finland "Adult vascular endothelial stem cells (VESCs)“ |
| 23 NOV |
Phillippe Jay Institute for Functional Genomics, Montpellier, France "Quiescent stem cells and the immortal:DNA strand in the intestinal epithelium: Rest in peace?" |
2011
| 21 JAN |
Hans- Reimer Rodewald DKFZ, Cellular Immunology, Heidelberg, Germany "Origin and Transformation of T-Cell Progenitors" |
| 18 FEB |
Michael A. Milsom DKFZ and HI-Stem GmbH, Heidelberg, Germany "Lost in transplantation: Fanconi anemia as a model of defective hematopoietic stem cell maintenance" |
| 18 MAR |
Karl Lenhard Rudolph University of Ulm, Ulm, Germany "Batf defines a differentiation checkpoint limiting hematopoietic stem cell self renewal in response to DNA damage" |
| 20 MAY |
Takashi Hiiragi MPI Münster and EMBL Heidelberg, Germany “Stochastic processes in the developmentof pluripotency in vivo” |
| 17 JUN |
Andreas Wodarz University of Göttingen, Göttingen, Germany "Molecular control of cell polarity in epithelia and stem cells" |
| 15 JUL |
Lukas Sommer University of Zürich, Zürich, Switzerland "Neural Crest Stem Cells and Melanoma:a Likely Connection" |
| 16 SEP |
Christian Buske University of Ulm, Ulm, Germany "Developmental genes in acute myeloid leukemia: lessons from mice" |
| 21 OCT |
Robert Oostendorp Klinikum rechts der Isar, München, Germany "The intimate relationship between stem cells and their niche" |
| 18 NOV |
Hitoshi Niwa RIKEN Center for Developmental Biology, Minatojima Minamimachi Chuo-ku Kobe, Japan "Molecular mechanism governing cellular pluripotency of mouse embryonic stem cells" |
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Seminars
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