Ruprecht-Karls-Universität Heidelberg
Welcome to COS Heidelberg

The Centre for Organismal Studies (COS) Heidelberg aims to study organismic biology beyond the borders of organisational level. Research and teaching at COS is dedicated to study organismic biology from the basic molecular principles to cell biology, developmental biology and physiology both in plants and in animals and to further extend into evolution, biodiversity, systems biology and biotechnology.




Heidelberg University informs on the regulations during the Coronavirus pandemic and on study and research with family in times of Covid-19. Stay healthy!



PRESTO funding

Dongbo Shi, postdoc in the Greb lab, has won a PRESTO grant from the Japanese Science and Technology Agency (JST) for his project on continuous plant growth.



Upcoming Event:

COS Keynote

From single-cell multi-omics to gene regulatory networks and enhancer logic

Prof. Dr. Stein Aerts

Laboratory of Computational Biology, KU Leuven, Belgium


18th of May 2021 10:00 AM

online, tba

Recent Publications:
Koch, M.A.; Mobus, J.; Klocker, C.A.; Lippert, S.; Ruppert, L.; Kiefer, C. 2020 The Quaternary evolutionary history of Bristol rock cress (Arabis scabra, Brassicaceae), a Mediterranean element with an outpost in the north-western Atlantic region Ann Bot 126 1 103-118 doi: 10.1093/aob/mcaa053 [Link]
Waadt, R.; Koster, P.; Andres, Z.; Waadt, C.; Bradamante, G.; Lampou, K.; Kudla, J.; Schumacher, K. 2020 Dual-Reporting Transcriptionally Linked Genetically Encoded Fluorescent Indicators Resolve the Spatiotemporal Coordination of Cytosolic Abscisic Acid and Second Messenger Dynamics in Arabidopsis Plant Cell 32 8 2582-2601 doi: 10.1105/tpc.19.00892 [Link]
Grigaitis, P.; Starkuviene, V.; Rost, U.; Serva, A.; Pucholt, P.; Kummer, U. 2020 miRNA target identification and prediction as a function of time in gene expression data RNA Biol 17 7 990-1000 doi: 10.1080/15476286.2020.1748921 [Link]
Seleit, A.; Gross, K.; Onistschenko, J.; Woelk, M.; Autorino, C.; Centanin, L. 2020 Development and regeneration dynamics of the Medaka notochord Dev Biol 463 1 11-25 doi: 10.1016/j.ydbio.2020.03.001 [Link]
Sloan, J.; Hakenjos, J.P.; Gebert, M.; Ermakova, O.; Gumiero, A.; Stier, G.; Wild, K.; Sinning, I.; Lohmann, J.U. 2020 Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL Nat Commun 11 1 2223 doi: 10.1038/s41467-020-16024-y [Link]
Arendt, D. 2020 The Evolutionary Assembly of Neuronal Machinery Curr Biol 30 10 R603-R616 doi: 10.1016/j.cub.2020.04.008 [Link]
Carnesecchi, J.; Lohmann, I. 2020 Closing the gap: a roadmap to single-cell regulatory genomics Mol Syst Biol 16 5 e9497 doi: 10.15252/msb.20209497 [Link]
Sorge, S.; Theelke, J.; Yildirim, K.; Hertenstein, H.; McMullen, E.; Muller, S.; Altburger, C.; Schirmeier, S.; Lohmann, I. 2020 ATF4-Induced Warburg Metabolism Drives Over-Proliferation in Drosophila Cell Rep 31 7 107659 doi: 10.1016/j.celrep.2020.107659 [Link]
Nunes, T.D.G.; Zhang, D.; Raissig, M.T. 2020 Form, development and function of grass stomata Plant J 101 4 780-799 doi: 10.1111/tpj.14552 [Link]
Viol, L.; Hata, S.; Pastor-Peidro, A.; Neuner, A.; Murke, F.; Wuchter, P.; Ho, A.D.; Giebel, B.; Pereira, G. 2020 Nek2 kinase displaces distal appendages from the mother centriole prior to mitosis J Cell Biol 219 3 doi: 10.1083/jcb.201907136 [Link]
Rajab, H.; Khan, M.S.; Wirtz, M.; Malagoli, M.; Qahar, F.; Hell, R. 2020 Sulfur metabolic engineering enhances cadmium stress tolerance and root to shoot iron translocation in Brassica napus L Plant Physiol Biochem 152 32-43 doi: 10.1016/j.plaphy.2020.04.017 [Link]
Robinson, D.G. 2020 Plant Golgi ultrastructure J Microsc doi: 10.1111/jmi.12899 [Link]
Ivanov, R.; Robinson, D.G. 2020 EMAC, Retromer, and VSRs: do they connect? Protoplasma 257 6 1725-1729 doi: 10.1007/s00709-020-01543-8 [Link]
Robinson, D.G.; Aniento, F. 2020 A Model for ERD2 Function in Higher Plants Front. Plant Sci. 11 doi: 10.3389/fpls.2020.00343 [Link]
Robinson, D.G.; Aniento, F. 2020 A Model for ERD2 Function in Higher Plants Front Plant Sci 11 343 doi: 10.3389/fpls.2020.00343 [Link]
Walden, N.; German, D.A.; Wolf, E.M.; Kiefer, M.; Rigault, P.; Huang, X.-C.; Kiefer, C.; Schmickl, R.; Franzke, A.; Neuffer, B.; Mummenhoff, K.; Koch, M.A. 2020 Nested whole-genome duplications coincide with diversification and high morphological disparity in Brassicaceae Nat Commun 11 1 3795 doi: 10.1038/s41467-020-17605-7 [Link]
Robinson, D.G.; Draguhn, A.; Taiz, L. 2020 Plant "intelligence" changes nothing EMBO Rep 21 5 e50395 doi: 10.15252/embr.202050395 [Link]

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