Dr. Markus WirtzVeröffentlichungen
Artikel in wissenschaftlichen Zeitschriften
2020
Armbruster L, Linster E, Boyer JB, Brünje A, Eirich J, Stephan I, Bienvenut WV, Weidenhausen J, Meinnel T, Hell R, Sinning I, Finkemeier I, Giglione C, Wirtz M. (2020). NAA50 Is an enzymatically active N-alpha-acetyltransferase that is crucial fordevelopment and regulation of stress responses. Plant Physiol, 183: 1502-1516. Bienvenut WV, Brünje A, Boyer JB, Mühlenbeck JS, Bernal G, Lassowskat I, Dian C, Linster E, Dinh TV, Koskela MM, Jung V, Seidel J, Schyrba LK, Ivanauskaite A, Eirich J, Hell R, Schwarzer D, Mulo P, Wirtz M, Meinnel T, Giglione C, Finkemeier I. (2020). Dual lysine and N-terminal acetyltransferases reveal the complexity underpinning protein acetylation. Mol Syst Biol, 16: e9464. Rajab H, Khan MS, Wirtz M, Malagoli M, Qahar F, Hell R. (2020). Sulfur metabolic engineering enhances cadmium stress tolerance and root to shoot iron translocation in Brassica napus L. Plant Physiol Biochem, 152: 32-43. Huber M, Bienvenut WV, Linster E, Stephan I, Armbruster L, Sticht C, Layer D, Lapouge K, Meinnel T, Sinning I, Giglione C, Hell R, Wirtz M. (2020). NatB-Mediated N-Terminal Acetylation Affects Growth and Biotic Stress Responses. Plant Physiol, 182: 792-806. Nietzel T, Mostertz J, Ruberti C, Nee G, Fuchs P, Wagner S, Moseler A, Müller-Schüssele SJ, Benamar A, Poschet G, Büttner M, Müller IM, Lillig CH, Macherel D, Wirtz M, Hell R, Finkemeier I, Meyer AJ, Hochgräfe F, Schwarzländer M. (2020). Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination. Proc Natl Acad Sci USA, 117: 741-751. Linster E, Layer D, Bienvenut WV, Dinh TV, Weyer FA, Leemhuis W, Brünje A, Hoffrichter M, Miklankova P, Kopp J, Lapouge K, Sindlinger J, Schwarzer D, Meinnel T, Finkemeier I, Giglione C, Hell R, Sinning I, Wirtz M. (2020). The Arabidopsis N-alpha-acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response. New Phytol, 228: 554-569.2019
Armbruster L, Uslu VV, Wirtz M, Hell R.(2019). The Recovery from Sulfur Starvation Is Independent from the mRNA Degradation Initiation Enzyme PARN in Arabidopsis. Plants, 8: 380. Marty L, Bausewein D, Müller C, Bangash SAK, Moseler A, Schwarzländer M, Müller-Schüssele SJ, Zechmann B, Riondet C, Balk J, Wirtz M, Hell R, Reichheld JP, Meyer AJ.(2019). Arabidopsis glutathione reductase 2 is indispensable in plastids, while mitochondrial glutathione is safeguarded by additional reduction and transport systems. New Phytol., 224: 1569-1584. Rajab H, Khan MS, Malagoli M, Hell R, Wirtz M. (2019). Sulfate-Induced Stomata Closure Requires the Canonical ABA Signal Transduction Machinery. Plants, 8: 21. Yang Y, Lenherr ED, Gromes R, Wang S, Wirtz M, Hell R, Peskan-Berghöfer T, Scheffzek K, Rausch T. (2019). Plant glutathione biosynthesis revisited: redox-mediated activation of glutamylcysteine ligase does not require homo-dimerization. Biochem. J., 476: 1191-1203. Chen Z, Zhao PX, Miao ZQ, Qi GF, Wang Z, Yuan Y, Ahmad N, Cao MJ, Hell R, Wirtz M, Xiang CB. (2019). SULTR3s Function in Chloroplast Sulfate Uptake and Affect ABA Biosynthesis and the Stress Response. Plant Physiol., 180: 593-604. Feldman-Salit A, Veith N, Wirtz M, Hell R, Kummer U. (2019). Distribution of control in the sulfur assimilation in Arabidopsis thaliana depends on environmental conditions. New Phytol., 222: 1392-1404. Zhang H, Linster E, Gannon L, Leemhuis W, Rundle CA, Theodoulou FL, Wirtz M. (2019). Tandem Fluorescent Protein Timers for Noninvasive Relative Protein Lifetime Measurement in Plants. Plant Physiol., 180: 718-731. Linzner N, Loi VV, Fritsch VN, Tung QN, Stenzel S, Wirtz M, Hell R, Hamilton CJ, Tedin K, Fulde M, Antelmann H. (2019). Staphylococcus aureus Uses the Bacilliredoxin (BrxAB)/Bacillithiol Disulfide Reductase (YpdA) Redox Pathway to Defend Against Oxidative Stress Under Infections. Front Microbiol., 10: 1355. Goslin K, Eschen-Lippold L, Naumann C, Linster E, Sorel M, Klecker M, de Marchi R, Kind A, Wirtz M, Lee J, Dissmeyer N, Graciet E. (2019). Differential N-end Rule Degradation of RIN4/NOI Fragments Generated by the AvrRpt2 Effector Protease. Plant Physiol., 180:2272-2289.2018
Dong, Y., Teleman, A.A., Jedmowski, C., Wirtz, M., Hell, R. (2018). The Arabidopsis THADA homologue modulates TOR activity and cold acclimation Plant Biol., 1: 77-83. Koskela, M.M., Brünje, A., Ivanauskaite, A., Grabsztunowicz, M., Lassowskat, I., Neumann, U., Dinh, T.V., Sindlinger, J., Schwarzer, D., Wirtz, M., Tyystjärvi, E., Finkemeier, I., Mulo, P. (2018). Chloroplast Acetyltransferase NSI Is Required for State Transitions in Arabidopsis thaliana. Plant Cell, 30: 1695-1709. Linster, E., Wirtz, M. (2018). N-terminal acetylation: an essential protein modification emerges as an important regulator of stress responses. J. Exp. Bot., 69: 4555-4568. Speiser, A., Silbermann, M., Dong, Y., Haberland, S., Uslu, V.V., Wang, S., Bangash, S.A.K., Reichelt, M., Meyer, A.J., Wirtz, M, Hell, R. (2018). Sulfur Partitioning between Glutathione and Protein Synthesis Determines Plant Growth. Plant Physiol., 177: 927-937.2017
Dong, Y., Silbermann, M., Speiser, A., Forieri, I., Linster, E., Poschet, G., Allboje Samami, A., Wanatabe, M., Sticht, C., Teleman, A.A., Deragon, J.-M., Saito, K., Hell, R., Wirtz, M. (2017). Sulfur availability regulates plant growth via glucose-TOR signaling. Nature Commun., 8: 1174. Forieri, I., Sticht, C., Reichelt, M., Gretz, N., Hawkesford, M.J., Malagoli, M., Wirtz, M., Hell, R. (2017). System analysis of metabolism and the transcriptome in Arabidopsis thaliana roots reveals differential co-regulation upon iron, sulfur and potassium deficiency. Plant Cell Environ., 40: 95-107. Giaretta, S., Prasad, D., Forieri, I., Vamerali, T., Trentin, A.R., Wirtz, M., Hell, R., Masi, A. (2017). Apoplastic gamma-glutamyl transferase activity encoded by GGT1 and GGT2 is important for vegetative and generative development. Plant Physiol Biochem., 115: 44-56. Hillion, M., Bernhardt, J., Busche, T., Rossius, M., Maass, S., Becher, D., Rawat, M., Wirtz, M., Hell, R., Ruckert, C., Kalinowski, J., Antelmann, H. (2017). Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress. Sci. Rep., 7: 1195. Hillion, M., Imber, M., Pedre, B., Bernhardt, J., Saleh, M., Loi, V.V., Maass, S., Becher, D., Astolfi Rosado, L., Adrian, L., Weise, C., Hell, R., Wirtz, M., Messens, J., Antelmann, H. (2017). The glyceraldehyde-3-phosphate dehydrogenase GapDH of Corynebacterium diphtheriae is redox-controlled by protein S-mycothiolation under oxidative stress. Sci. Rep., 7: 5020. Malcheska, F., Ahmad, A., Batool, S., Müller, H.M., Ludwig-Müller, J., Kreuzwieser, J., Randewig, D., Hänsch, R., Mendel, R.R., Hell, R., Wirtz, M., Geiger, D., Ache, P., Hedrich, R., Herschbach, C., Rennenberg, H. (2017). Drought-Enhanced Xylem Sap Sulfate Closes Stomata by Affecting ALMT12 and Guard Cell ABA Synthesis. Plant Physiol., 174: 798-814. Mueller, S.M., Wang, S., Telman, W., Liebthal, M., Schnitzer, H., Viehhauser, A., Sticht, C., Delatorre, C., Wirtz, M., Hell, R., Dietz, K.J. (2017). The redox-sensitive module of cyclophilin 20-3, 2-cysteine peroxiredoxin and cysteine synthase integrates sulfur metabolism and oxylipin signaling in the high light acclimation response. Plant J., 91: 995-1014.2016
Groth, M., Moissiard, G., Wirtz, M., Wang, H., Garcia-Salinas, C., Ramos-Parra, P.A., Bischof, S.,Feng, S., Cokus, S.J., John, A., Smith, D.C.. Zhai, J., Hale, C.J., Long, J.A., Hell, R., Diaz de la Garza, R.I., Jacobsen, S.E. (2016). MTHFD1 controls DNA methylation in Arabidopsis. Nature Commun., 7: 11640. Pfeiffer, A. Janocha, D., Dong, Y., Medzihradszky, A., Schone, S., Daum, G., Suzaki, T., Forner, J., Langenecker, T., Rempel, E., Schmid, M., Wirtz, M., Hell, R., Lohmann, J. U. (2016). Integration of light and metabolic signals for stem cell activation at the shoot apical meristem. Elife, 5: e17023. Huang, X. Y., Chao, D. Y., Koprivova, A., Danku, J., Wirtz, M., Muller, S., Sandoval, F. J., Bauwe, H., Roje, S., Dilkes, B., Hell, R., Kopriva, S., Salt, D. E. (2016). Nuclear Localised MORE SULPHUR ACCUMULATION1 Epigenetically Regulates Sulphur Homeostasis in Arabidopsis thaliana. PLoS Genet., 12: e1006298. Kovacs, I., Holzmeister, C., Wirtz, M., Geerlof, A., Fröhlich, T., Römling, G., Kuruthukulangarakoola, G.T., Linster, E., Hell, R., Arnold, G.J. Durner, J., Lindermayr., C. (2016). ROS-Mediated Inhibition of S-nitrosoglutathione Reductase Contributes to the Activation of Anti-oxidative Mechanisms. Front. Plant Sci., 7: 1669. Ahmad, N., Malagoli, M., Wirtz, M., Hell, R. (2016). Drought stress in maize causes differential acclimation responses of glutathione and sulfur metabolism in leaves and roots. BMC Plant Biol., 16:247. Huang, L. J., Li, N., Thurow, C., Wirtz, M., Hell, R., Gatz, C. (2016). Ectopically expressed glutaredoxin ROXY19 negatively regulates the detoxification pathway in Arabidopsis thaliana. BMC Plant Biol., 16: 200.2015
Linster, E., Stephan, I., Bienvenut, W.V., Maple-Grodem, J., Myklebust, L.M.., Huber, M., Reichelt, M., Sticht, C., Geir Moller, S., Meinnel, T., Arnesen, T., Giglione, C., Hell, R., Wirtz, M. (2015). Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in Arabidopsis. Nature Commun., 6: 7640. Xu, F., Huang, Y., Li, L., Gannon, P., Linster, E., Huber, M., Kapos, P., Bienvenut, W., Polevoda, B., Meinnel, T., Hell, R., Giglione, C., Zhang, Y., Wirtz, M., Chen, S., Li, X. (2015). Two N-terminal acetyltransferases antagonistically regulate the stability of a nod-like receptor in Arabidopsis Plant Cell, 27: 1547-62. Timm, S., Wittmiss, M., Gamlien, S., Ewald, R., Florian, A., Frank, M., Wirtz, M., Hell, R., Fernie, A. R., Bauwe, H. (2015). Mitochondrial Dihydrolipoyl Dehydrogenase Activity Shapes Photosynthesis and Photorespiration of Arabidopsis thaliana. Plant Cell, 27: 1968-1984. Dinh, T. V., Bienvenut, W. V., Linster, E., Feldman-Salit, A., Jung, V. A., Meinnel, T. Hell, R., Giglione, C., Wirtz, M. (2015). Molecular identification and functional characterization of the first N-alpha-acetyltransferase in plastids by global acetylome profiling. Proteomics, 15: 2426-2435. Yang. Y., M Pollard, A., Höfler, C., Poschet, G., Wirtz, M., Hell, R., Sourjik, V. (2015). Relation between chemotaxis and consumption of amino acids in bacteria. Mol Microbiol., 96: 1272-1282. Birke, H., Hildebrandt, T. M., Wirtz, M., Hell, R. (2015). Sulfide detoxification in plant mitochondria. Methods Enzymol, 555: 271-286. Tavares, S., Wirtz, M., Beier, M. P., Bogs, J., et al. (2015). Characterization of the serine acetyltransferase gene family of Vitis vinifera uncovers differences in regulation of OAS synthesis in woody plants. Front Plant Sci 2015, 6: 74. Speiser, A., Haberland, S., Watanabe, M., Wirtz, M., et al. (2015). The significance of cysteine synthesis for acclimation to high light conditions. Front Plant Sci 2014, 5, 776. Birke H, De Kok LJ, Wirtz M, Hell R. (2015). The Role of Compartment-Specific Cysteine Synthesis for Sulfur Homeostasis During H2S Exposure in Arabidopsis. Plant Cell Physiol. 65: 358-367.2014
Salbitani G, Wirtz M, Hell R., Carfagna, S (2014). Affinity Purification of O-Acetylserine(thiol)lyase from Chlorella sorokiniana by Recombinant Proteins from Arabidopsis thaliana. Metabolites. 4: 629-639. Krüssel L, Junemann J, Wirtz M, Birke H, Thornton JD, Browning LW, Poschet G, Hell R, Balk J, Braun HP, Hildebrandt TM (2014). The Mitochondrial Sulfur Dioxygenase ETHYLMALONIC ENCEPHALOPATHY PROTEIN1 Is Required for Amino Acid Catabolism during Carbohydrate Starvation and Embryo Development in Arabidopsis. Plant Physiol. 165: 92-104. Cao M, Wang Z, Zhao Q, Mao J, Speiser A, Wirtz M, Hell R, Zhu J-K, Xiang CB. (2014). Sulfate availability affects ABA levels and germination response to ABA and salt stress in Arabidopsis thaliana. Plant J. 77: 604-615. Lee CP, Wirtz M, Hell R. (2014). Evidence for several cysteine transport mechanisms in the mitochondrial membranes of Arabidopsis thaliana. Plant Cell Physiol. 55: 64-73.2013
Birke H, Wirtz M, Hell R. (2013). Successful fertilization requires the presence of at least one major O-acetylserine(thiol)lyase for cysteine synthesis in pollen of Arabidopsis. Plant Physiol. 163: 959-972. Cao MJ, Wang Z, Wirtz M, Hell R, Oliver DJ, Xiang CB. (2013). SULTR3;1 is a chloroplast-localized sulfate transporter in Arabidopsis thaliana. Plant J. 73: 607 - 616. Forieri I, Wirtz M, Hell R. (2013). Towards new perspectives on the interaction of iron and sulfur metabolism in plants. Front Plant Sci. Oct 2;4:357. doi: 10.3389/fpls.2013.00357. Sauter M, Moffatt B, Saechao MC, Hell R, Wirtz M. (2013). Methionine salvage and S-adenosylmethionine: essential links between sulfur, ethylene and polyamine biosynthesis. Biochem J. 451: 145-154. Chan KX, Wirtz M, Phua SY, Estavillo GM, Pogson BJ. (2013). Balancing metabolites in drought: the sulfur assimilation conundrum. Trends Plant Sci. 18: 18 - 29.2012
Van de Poel B, Bulens I, Markoula A, Hertog M, Dreesen R, Wirtz M, Vandoninck S, Oppermann Y, Keulemans W, Hell R, Waelkens E, De Proft MP, Sauter M, Nicolai BM, Geeraerd AH. (2012). Targeted systems biology profiling of tomato fruit reveals coordination of the Yang cycle and a distinct regulation of ethylene biosynthesis during post-climacteric ripening. Plant Physiol. 160: 1498 - 1514. Schiavon M, Galla G, Wirtz M, Pilon-Smits EA, Telatin V, Quaggiotti S, Hell R, Barcaccia G, Malagoli M. (2012). Transcriptome profiling of genes differentially modulated by sulfur and chromium identifies potential targets for phytoremediation and reveals a complex S-Cr interplay on sulfate transport regulation in B. juncea. J Hazard Mater. 239-240: 192-205. Birke H, Haas FH, De Kok LJ, Balk J, Wirtz M, Hell R. (2012). Cysteine biosynthesis, in concert with a novel mechanism, contributes to sulfide detoxification in mitochondria of Arabidopsis thaliana. Biochem J. 445: 275-283. Birke H, Müller SJ, Rother M, Zimmer AD, Hoernstein SN, Wesenberg D, Wirtz M, Krauss GJ, Reski R, Hell R. (2012). The relevance of compartmentation for cysteine synthesis in phototrophic organisms. Protoplasma 249: 147-155 Bok-Rye L, Huseby S, Koprivova A, Chetelat A, Wirtz M, Mugford ST, Navid E, Brearley C, Saha S, Mithen R, Hell R, Farmer EE, Kopriva S (2012). Effects of fou8/fry1 Mutation on Sulfur Metabolism: Is Decreased Internal Sulfate the Trigger of Sulfate Starvation Response? PLoS ONE. 7 (6): e39425. Haydon MJ, Kawachi M, Wirtz M, Hillmer S, Hell R, Krämer U. (2012). Vacuolar Nicotianamine Has Critical and Distinct Roles under Iron Deficiency and for Zinc Sequestration in Arabidopsis. Plant Cell. 24: 724-737 Kruse C, Haas FH, Jost R, Reiser B, Reichelt M, Wirtz M, Gershenzon J, Schnug E, Hell R. (2012). Improved sulfur nutrition provides the basis for enhanced production of sulfur-containing defense compounds in Arabidopsis thaliana upon inoculation with Alternaria brassicicola. J Plant Physiol.169: 740-743 Feldman-Salit A, Wirtz M, Lenherr ED, Throm C, Hothorn M, Scheffzek K, Hell R, Wade RC. (2012). Allosterically Gated Enzyme Dynamics in the Cysteine Synthase Complex Regulate Cysteine Biosynthesis in Arabidopsis thaliana. Structure. 20:292-302. Schiavon, M., Pittarello, M., Pilon-Smits, E.A.H., Wirtz, M., Hell, R., Malagoli, M. (2012). Selenate and molybdate alter sulfate transport and assimilation in Brassica juncea L. Czern.: Implications for phytoremediation. Environmental and Experimental Botany. 75: 41-51. Waduwara-Jayabahu I, Oppermann Y, Wirtz M, Hull ZT, Schoor S, Plotnikov AN, Hell R, Sauter M, Moffatt BA. (2012). Recycling of methylthioadenosine is essential for normal vascular development and reproduction in Arabidopsis. Plant Physiol.158: 1728-1744 Wirtz M, Beard KFM, Lee CP, Boltz A, Schwarzlaender M, Fuchs C, Meyer AJ, Heeg C, Sweetlove LJ, Ratcliffe RG Hell R. (2012). Mitochondrial cysteine synthase complex regulates O-acetylserine biosynthesis in plants J Biol Chem. 287: 27941-27947.2011
Wirtz M, Hell R. (2011). Molecular Biology, Biochemistry and Cellular Physiology of Cysteine Metabolism in Arabidopsis thaliana. The Arabidopsis Book. 9: e0154.2011. Estavillo GM, Crisp PA, Pornsiriwong W, Wirtz M, Collinge D, Carrie C, Giraud E, Whelan J, David P, Javot H, Brearley C, Hell R, Marin E, Pogson BJ. (2011). Evidence for a SAL1-PAP Chloroplast Retrograde Pathway That Functions in Drought and High Light Signaling in Arabidopsis. Plant Cell. 23:3992-4012 Abstract Hsu FC, Wirtz M, Heppel SC, Bogs J, Krämer U, Khan MS, Bub A, Hell R, Rausch T. (2011). Generation of Se-fortified broccoli as functional food: impact of Se fertilization on S metabolism. Plant Cell Environ. 34:192-207.2010
Wirtz M, Birke H, Heeg C, Müller C, Hosp F, Throm C, König S, Feldman-Salit A, Rippe K, Petersen G, Wade RC, Rybin V, Scheffzek K, Hell R. (2010). Structure and function of the hetero-oligomeric cysteine synthase complex in plants. J Biol Chem. 285:32810-7. Zuber H, Davidian JC, Aubert G, Aime D, Belghazi M, Lugan R, Heintz D, Wirtz M, Hell R, Thompson R, Gallardo K. (2010). The seed composition of Arabidopsis mutants for the group 3 sulfate transporters indicates a role in sulfate translocation within developing seeds. Plant Physiol. 154:913-26. Wirtz M, Heeg C, Samami AA, Ruppert T, Hell R. (2010). Enzymes of cysteine synthesis show extensive and conserved modifications patterns that include N(alpha)-terminal acetylation. Amino Acids. 39:1077-86. Zuber H, Davidian JC, Wirtz M, Hell R, Belghazi M, Thompson R, Gallardo K. (2010). Sultr4;1 mutant seeds of Arabidopsis have an enhanced sulphate content and modified proteome suggesting metabolic adaptations to altered sulphate compartmentalization. BMC Plant Biol. 10:78. Khan MS, Haas FH, Samami AA, Gholami AM, Bauer A, Fellenberg K, Reichelt M, Hänsch R, Mendel RR, Meyer AJ, Wirtz M, Hell R. (2010). Sulfite reductase defines a newly discovered bottleneck for assimilatory sulfate reduction and is essential for growth and development in Arabidopsis thaliana. Plant Cell. 22:1216-31. Bürstenbinder K, Waduwara I, Schoor S, Moffatt BA, Wirtz M, Minocha SC, Oppermann Y, Bouchereau A, Hell R, Sauter M. (2010). Inhibition of 5'-methylthioadenosine metabolism in the Yang cycle alters polyamine levels, and impairs seedling growth and reproduction in Arabidopsis. Plant J. 62:977-88.2009
Tabe L, Wirtz M, Molvig L, Droux M, Hell R. (2009). Overexpression of serine acetlytransferase produced large increases in O-acetylserine and free cysteine in developing seeds of a grain legume. J Exp Bot. 61:721-33. Bräutigam K, Dietzel L, Kleine T, Ströher E, Wormuth D, Dietz KJ, Radke D, Wirtz M, Hell R, Dörmann P, Nunes-Nesi A, Schauer N, Fernie AR, Oliver SN, Geigenberger P, Leister D, Pfannschmidt T. (2009). Dynamic plastid redox signals integrate gene expression and metabolism to induce distinct metabolic states in photosynthetic acclimation in Arabidopsis. Plant Cell. 21:2715-32. Marty L, Siala W, Schwarzländer M, Fricker MD, Wirtz M, Sweetlove LJ, Meyer Y, Meyer AJ, Reichheld JP, Hell R. (2009). The NADPH-dependent thioredoxin system constitutes a functional backup for cytosolic glutathione reductase in Arabidopsis. Proc Natl Acad Sci U S A. 106:9109-14. Roeder S, Dreschler K, Wirtz M, Cristescu SM, van Harren FJ, Hell R, Piechulla B. (2009). SAM levels, gene expression of SAM synthetase, methionine synthase and ACC oxidase, and ethylene emission from N. suaveolens flowers. Plant Mol Biol. 70:535-46. Mugford SG, Yoshimoto N, Reichelt M, Wirtz M, Hill L, Mugford ST, Nakazato Y, Noji M, Takahashi H, Kramell R, Gigolashvili T, Flügge UI, Wasternack C, Gershenzon J, Hell R, Saito K, Kopriva S. (2009). Disruption of adenosine-5'-phosphosulfate kinase in Arabidopsis reduces levels of sulfated secondary metabolites. Plant Cell. 21:910-27. Klatte M, Schuler M, Wirtz M, Fink-Straube C, Hell R, Bauer P. (2009). The analysis of Arabidopsis nicotianamine synthase mutants reveals functions for nicotianamine in seed iron loading and iron deficiency responses. Plant Physiol. 150:257-71.2008
Feldman-Salit A, Wirtz M, Hell R, Wade RC. (2008). A mechanistic model of the cysteine synthase complex. J Mol Biol. 386:37-59. Haas FH, Heeg C, Queiroz R, Bauer A, Wirtz M, Hell R. (2008). Mitochondrial serine acetyltransferase functions as a pacemaker of cysteine synthesis in plant cells. Plant Physiol. 148:1055-67. Schiavon M, Pilon-Smits EA, Wirtz M, Hell R, Malagoli M. (2008). Interactions between chromium and sulfur metabolism in Brassica juncea. J Environ Qual. 37:1536-45. Rouached H, Wirtz M, Alary R, Hell R, Arpat AB, Davidian JC, Fourcroy P, Berthomieu P. (2008). Differential regulation of the expression of two high-affinity sulfate transporters, SULTR1.1 and SULTR1.2, in Arabidopsis. Plant Physiol. 147:897-911. Heeg C, Kruse C, Jost R, Gutensohn M, Ruppert T, Wirtz M, Hell R. (2008). Analysis of the Arabidopsis O-acetylserine(thiol)lyase gene family demonstrates compartment-specific differences in the regulation of cysteine synthesis. Plant Cell. 20:168-85.2007
Pasternak M, Lim B, Wirtz M, Hell R, Cobbett CS, Meyer AJ. (2007). Restricting glutathione biosynthesis to the cytosol is sufficient for normal plant development. Plant J. 53:999-1012. Schiavon M, Wirtz M, Borsa P, Quaggiotti S, Hell R, Malagoli M. (2007). Chromate differentially affects the expression of a high-affinity sulfate transporter and isoforms of components of the sulfate assimilatory pathway in Zea mays (L.). Plant Biol 9:662-71. Rzewuski G, Cornell KA, Rooney L, Bürstenbinder K, Wirtz M, Hell R, Sauter M. (2007). OsMTN encodes a 5'-methylthioadenosine nucleosidase that is up-regulated during submergence-induced ethylene synthesis in rice (Oryza sativa L.). J Exp Bot. 58:1505-14. Lang C, Popko J, Wirtz M, Hell R, Herschbach C, Kreuzwieser J, Rennenberg H, Mendel RR, Hänsch R. (2007). Sulphite oxidase as key enzyme for protecting plants against sulphur dioxide. Plant Cell Environ. 30:447-55. Wirtz M, Hell R. (2007). Dominant-negative modification reveals the regulatory function of the multimeric cysteine synthase protein complex in transgenic tobacco. Plant Cell. 19:625-39.2006
Bürstenbinder K, Rzewuski G, Wirtz M, Hell R, Sauter M. (2006). The role of methionine recycling for ethylene synthesis in Arabidopsis. Plant J. 49:238-49.2005
Wirtz M, Hell R. (2005). Functional analysis of the cysteine synthase protein complex from plants: structural, biochemical and regulatory properties. J Plant Physiol. 163:273-86. Jost R, Altschmied L, Bloem E, Bogs J, Gershenzon J, Hähnel U, Hänsch R, Hartmann T, Kopriva S, Kruse C, Mendel RR, Papenbrock J, Reichelt M, Rennenberg H, Schnug E, Schmidt A, Textor S, Tokuhisa J, Wachter A, Wirtz M, Rausch T, Hell R.(2005). Expression profiling of metabolic genes in response to methyl jasmonate reveals regulation of genes of primary and secondary sulfur-related pathways in Arabidopsis thaliana. Photosynth Res. 86:491-508.2004
Fey V, Wagner R, Braütigam K, Wirtz M, Hell R, Dietzmann A, Leister D, Oelmüller R, Pfannschmidt T. (2004). Retrograde plastid redox signals in the expression of nuclear genes for chloroplast proteins of Arabidopsis thaliana. J Biol Chem. 280:5318-28. Buchner P, Stuiver CE, Westerman S, Wirtz M, Hell R, Hawkesford MJ, De Kok LJ. (2004). Regulation of sulfate uptake and expression of sulfate transporter genes in Brassica oleracea as affected by atmospheric H(2)S and pedospheric sulfate nutrition. Plant Physiol. 136:3396-408. Wirtz M, Droux M, Hell R. (2004). O-acetylserine (thiol) lyase: an enigmatic enzyme of plant cysteine biosynthesis revisited in Arabidopsis thaliana. J Exp Bot. 55:1785-98. Hartmann T, Hönicke P, Wirtz M, Hell R, Rennenberg H, Kopriva S. (2004). Regulation of sulphate assimilation by glutathione in poplars (Populus tremula x P. alba) of wild type and overexpressing gamma-glutamylcysteine synthetase in the cytosol. J Exp Bot. 55:837-45.2003
Wirtz M, Hell R. (2003). Production of cysteine for bacterial and plant biotechnology: application of cysteine feedback-insensitive isoforms of serine acetyltransferase. Amino Acids 24:195-203.2002
Hell R, Jost R, Berkowitz O, Wirtz M. (2002). Molecular and biochemical analysis of the enzymes of cysteine biosynthesis in the plant Arabidopsis thaliana. Amino Acids 22:245-57. Berkowitz O, Wirtz M, Wolf A, Kuhlmann J, Hell R. (2002). Use of biomolecular interaction analysis to elucidate the regulatory mechanism of the cysteine synthase complex from Arabidopsis thaliana. J Biol Chem. 277:30629-34.2001
Wirtz M, Berkowitz O, Droux M, Hell R. (2001). The cysteine synthase complex from plants. Mitochondrial serine acetyltransferase from Arabidopsis thaliana carries a bifunctional domain for catalysis and protein-protein interaction. Eur J Biochem. 268:686-93.2000
Jost R, Berkowitz O, Wirtz M, Hopkins L, Hawkesford MJ, Hell R. (2000). Genomic and functional characterization of the oas gene family encoding O-acetylserine (thiol) lyases, enzymes catalyzing the final step in cysteine biosynthesis in Arabidopsis thaliana. Gene. 253:237-47.Buchbeiträge und Berichte
Hell, R. Khan, M.S., Wirtz, M. (2010) Cellular Biology of Sulfur and Its Functions in Plants.
In: Cell Biology of Metals and Nutrients. Springer, Berlin: 243-279
Haas, F., Queiroz, R., Schanné, M., Wirtz, M., Hell, R. (2009) High resolution gene expression analysis
of the sulfur-dependent transcriptome.
In: Sirko et al. (eds) Sulfur Metabolism in Higher plants. Markgraf Publishers, Germany, pp.147-152
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