The plastid cysteine synthase complex regulates ABA biosynthesis and stomatal closure in Arabidopsis | Sun, S. K., Ahmad, N., Callenius, H., Rajab, H., Uslu, V. V., Cruz Cruz, J. R., Zhao, F. J., Wirtz, M. & Hell, R. | | Nature Communications: 16, 8960 | |
A GLUTAMATE CYSTEINE LIGASE Gene StGSH1 Regulated by StERF10 Enhanced Glutathione Accumulation and Adaptation to Low Phosphorus Stress in Potato | Tian, X., Li, M., Huang, X., Wirtz, M., Zheng, X., Fan, S., Tian, J., Liu, S., Liu, Z. & Zhao, H. | | Advanced Science: 13, e09143 | |
Biofortifying multiple micronutrients and decreasing arsenic accumulation in rice grain simultaneously by expressing a mutant allele of OAS-TL gene | Xu, X., Sun, S.K., Gao, A., Huang, X.Y., Wirtz, M., Hell, R. & Zhao, F.J. | | New Phytologist, 244: 2382-2395 | |
HYPK controls stability and catalytic activity of the N-terminal acetyltransferase A in Arabidopsis thaliana | Gong, X., Boyer, J.-B., Gierlich, S., Po?oga, M., Weidenhausen, J., Sinning, I., Meinnel, T., Giglione, C., Wang, Y., Hell, R. & Wirtz, M. | | | |
Light changes promote distinct responses of plastid protein acetylation marks | Eirich, J., Boyer, J.-B., Armbruster, L., Ivanauskaite, A., De La Torre, C., Meinnel, T., Wirtz, M., Mulo, P., Finkemeier, I. & Giglione, C. | | Molecular & Cellular Proteomics, 100845 | |
The vacuolar sulfate transporter PsSULTR4 is a key determinant of seed yield and protein composition in pea | Bachelet, F., Sanchez, M., Aimé, D., Naudé, F., Rossin, N., Ourry, A., Deulvot, C., Le Signor, C., Vernoud, V., Neiers, F., Wirtz, M. & Gallardo-Guerrero, K. | | The Plant Journal: 119, 2919-2936 | |
Na-acetyltransferase NAA50 mediates plant immunity independent of the Na-acetyltransferase A complex | Armbruster, L., Pozoga, M., Wu, Z., Eirich, J., Thulasi Devendrakumar, K., De La Torre, C., Miklankova, P., Huber, M., Bradic, F., Poschet, G., Weidenhausen, J., Merker, S., Ruppert, T., Sticht, C., Sinning, I., Finkemeier, I., Li, X., Hell, R. & Wirtz, M. | | Plant Physiology: 195, 3097-3118 | |
Relative Protein Lifetime Measurement in Plants Using Tandem Fluorescent Protein Timers | Zhang, H., Linster, E., Wirtz, M. & Theodoulou, F.L. | | Methods Mol Biol: 2581, 201-220 | |
Dynamic association of the plastid localized cysteine synthase complex is vital for efficient cysteine production, photosynthesis, and granal thylakoid formation in transgenic tobacco | Wirtz, M., Leemhuis, W. & Hell, R. | | | |
Mitochondrial alternative NADH dehydrogenases NDA1 and NDA2 promote survival of reoxygenation stress in Arabidopsis by safeguarding photosynthesis and limiting ROS generation | Jethva, J., Lichtenauer, S., Schmidt-Schippers, R., Steffen-Heins, A., Poschet, G., Wirtz, M., van Dongen, J.T., Eirich, J., Finkemeier, I., Bilger, W., Schwarzländer, M. & Sauter, M. | | | |
Nt-acetylation-independent turnover of SQUALENE EPOXIDASE 1 by Arabidopsis DOA10-like E3 ligases | Etherington, R.D., Bailey, M., Boyer, J.B., Armbruster, L., Cao, X., Coates, J.C., Meinnel, T., Wirtz, M., Giglione, C. & Gibbs, D.J. | | Plant Physiol: 193, 2086-2104 | |
Translational fidelity and growth of Arabidopsis require stress-sensitive diphthamide biosynthesis | Zhang, H., Quintana, J., Ütkür, K., Adrian, L., Hawer, H., Mayer, K., Gong, X., Castanedo, L., Schulten, A., Janina, N., Peters, M., Wirtz, M., Brinkmann, U., Schaffrath, R. & Krämer, U. | | | |
The cytosolic Arabidopsis thaliana cysteine desulfurase ABA3 delivers sulfur to the sulfurtransferase STR18 | Selles, B., Moseler, A., Caubrière, D., Sun, S.-K., Ziesel, M., Dhalleine, T., Hériché, M., Wirtz, M., Rouhier, N. & Couturier, J. | | | |
MCU proteins dominate in vivo mitochondrial Ca2+ uptake in Arabidopsis roots | Ruberti, C., Feitosa-Araujo, E., Xu, Z., Wagner, S., Grenzi, M., Darwish, E., Lichtenauer, S., Fuchs, P., Parmagnani, A.S., Balcerowicz, D., Schoenaers, S., de la Torre, C., Mekkaoui, K., Nunes-Nesi, A., Wirtz, M., Vissenberg, K., Van Aken, O., Hause, B., Costa, A. & Schwarzländer, M. | | Plant Cell: 34, 4428-4452 | |
From Nucleus to Membrane: A Subcellular Map of the N-Acetylation Machinery in Plants | Pozoga, M., Armbruster, L. & Wirtz, M. | | | |
HYPK promotes the activity of the N?-acetyltransferase A complex to determine proteostasis of nonAc-X2/N-degron-containing proteins | Miklánková, P., Linster, E., Boyer, J.B., Weidenhausen, J., Mueller, J., Armbruster, L., Lapouge, K., De La Torre, C., Bienvenut, W., Sticht, C., Mann, M., Meinnel, T., Sinning, I., Giglione, C., Hell, R. & Wirtz, M. | | | |
Cotranslational N-degron masking by acetylation promotes proteome stability in plants | Linster, E., Forero Ruiz, F.L., Miklankova, P., Ruppert, T., Mueller, J., Armbruster, L., Gong, X., Serino, G., Mann, M., Hell, R. & Wirtz, M. | | | |
Discriminative Long-Distance Transport of Selenate and Selenite Triggers Glutathione Oxidation in Specific Subcellular Compartments of Root and Shoot Cells in Arabidopsis | Khan, M.S., Soyk, A., Wolf, I., Peter, M., Meyer, A.J., Rausch, T., Wirtz, M. & Hell, R. | | Front Plant Sci: 13, 894479 | |
Disruption of the N?-Acetyltransferase NatB Causes Sensitivity to Reductive Stress in Arabidopsis thaliana | Huber, M., Armbruster, L., Etherington, R.D., De La Torre, C., Hawkesford, M.J., Sticht, C., Gibbs, D.J., Hell, R. & Wirtz, M. | | Front Plant Sci: 12, 799954 | |
OsHYPK-mediated protein N-terminal acetylation coordinates plant development and abiotic stress responses in rice | Gong, X., Huang, Y., Liang, Y., Yuan, Y., Liu, Y., Han, T., Li, S., Gao, H., Lv, B., Huang, X., Linster, E., Wang, Y., Wirtz, M. & Wang, Y. | | | |
Differential sensitivity of metabolic pathways in sugar beet roots to combined salt, heat, and light stress | García-Caparrós, P., Vogelsang, L., Persicke, M., Wirtz, M., Kumar, V. & Dietz, K.J. | | Physiol Plant: 174, e13786 | |
The plant TOR kinase tunes autophagy and meristem activity for nutrient stress-induced developmental plasticity | Dong, Y., Aref, R., Forieri, I., Schiel, D., Leemhuis, W., Meyer, C., Hell, R. & Wirtz, M. | | Plant Cell: 34, 3814-3829 | |
Structural and functional characterization of the N-terminal acetyltransferase NAA50 | Weidenhausen, J., Kopp, J., Armbruster, L., Wirtz, M., Lapouge, K. & Sinning, I. | | | |
Metabolite Profiling in Arabidopsis thaliana with Moderately Impaired Photorespiration Reveals Novel Metabolic Links and Compensatory Mechanisms of Photorespiration | Timm, S., Nunes-Nesi, A., Florian, A., Eisenhut, M., Morgenthal, K., Wirtz, M., Hell, R., Weckwerth, W., Hagemann, M., Fernie, A.R. & Bauwe, H. | | | |
A molecular switch in sulfur metabolism to reduce arsenic and enrich selenium in rice grain | Sun, S.K., Xu, X., Tang, Z., Tang, Z., Huang, X.Y., Wirtz, M., Hell, R. & Zhao, F.J. | | | |
GSNOR Contributes to Demethylation and Expression of Transposable Elements and Stress-Responsive Genes | Rudolf, E.E., Hüther, P., Forné, I., Georgii, E., Han, Y., Hell, R., Wirtz, M., Imhof, A., Becker, C., Durner, J. & Lindermayr, C. | | | |
The function of glutaredoxin GRXS15 is required for lipoyl-dependent dehydrogenases in mitochondria | Moseler, A., Kruse, I., Maclean, A.E., Pedroletti, L., Franceschetti, M., Wagner, S., Wehler, R., Fischer-Schrader, K., Poschet, G., Wirtz, M., Dormann, P., Hildebrandt, T.M., Hell, R., Schwarzlander, M., Balk, J. & Meyer, A.J. | | Plant Physiol: 186, 507-1525 | |
Micrografting Provides Evidence for Systemic Regulation of Sulfur Metabolism between Shoot and Root | Forieri, I., Aref, R., Wirtz, M. & Hell, R. | | | |
Sulfur metabolic engineering enhances cadmium stress tolerance and root to shoot iron translocation in Brassica napus L | Rajab, H., Khan, M.S., Wirtz, M., Malagoli, M., Qahar, F. & Hell, R. | | Plant Physiol & Biochem: 152, 32-43 | |
Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination | Nietzel, T., Mostertz, J., Ruberti, C., Née, G., Fuchs, P., Wagner, S., Moseler, A., Müller-Schüssele, S.J., Benamar, A., Poschet, G., Büttner, M., Møller, I.M., Lillig, C.H., Macherel, D., Wirtz, M., Hell, R., Finkemeier, I., Meyer, A.J., Hochgräfe, F. & Schwarzländer, M. | | Proc Natl Acad Sci U S A: 117, 741-751 | |
The Arabidopsis N?-acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response | Linster, E., Layer, D., Bienvenut, W.V., Dinh, T.V., Weyer, F.A., Leemhuis, W., Brünje, A., Hoffrichter, M., Miklankova, P., Kopp, J., Lapouge, K., Sindlinger, J., Schwarzer, D., Meinnel, T., Finkemeier, I., Giglione, C., Hell, R., Sinning, I. & Wirtz, M. | | New Phytologist: 228, 554-569 | |
NatB-Mediated N-Terminal Acetylation Affects Growth and Biotic Stress Responses | Huber, M., Bienvenut, W.V., Linster, E., Stephan, I., Armbruster, L., Sticht, C., Layer, D., Lapouge, K., Meinnel, T., Sinning, I., Giglione, C., Hell, R. & Wirtz, M. | | Plant Physiol: 182, 792-806 | |
Dual lysine and N-terminal acetyltransferases reveal the complexity underpinning protein acetylation | Bienvenut, W.V., Brünje, A., Boyer, J.-B., Mühlenbeck, J.S., Bernal, G., Lassowskat, I., Dian, C., Linster, E., Dinh, T.V., Koskela, M.M., Jung, V., Seidel, J., Schyrba, L.K., Ivanauskaite, A., Eirich, J., Hell, R., Schwarzer, D., Mulo, P., Wirtz, M., Meinnel, T., Giglione, C. & Finkemeier, I. | | Molecular Systems Biology: 16, e9464 | |
NAA50 Is an Enzymatically Active Na-Acetyltransferase That Is Crucial for Development and Regulation of Stress Responses | Armbruster, L., Linster, E., Boyer, J.-B., Brünje, A., Eirich, J., Stephan, I., Bienvenut, W.V., Weidenhausen, J., Meinnel, T., Hell, R., Sinning, I., Finkemeier, I., Giglione, C. & Wirtz, M. | | Plant Physiol: 183, 1502-1516 | |
Tandem Fluorescent Protein Timers for Noninvasive Relative Protein Lifetime Measurement in Plants | Zhang, H., Linster, E., Gannon, L., Leemhuis, W., Rundle, C.A., Theodoulou, F.L. & Wirtz, M. | | Plant Physiol: 180, 718-731 | |
Plant glutathione biosynthesis revisited: Redox-mediated activation of glutamylcysteine ligase does not require homo-dimerization | Yang, Y., Lenherr, E., Gromes, R., Wang, S., Wirtz, M., Hell, R., Peskan-Berghofer, T., Scheffzek, K. & Rausch, T. | | Biochem J: 476, 1191-1203 | |
Sulfate-Induced Stomata Closure Requires the Canonical ABA Signal Transduction Machinery | Rajab, H., Khan, M.S., Malagoli, M., Hell, R. & Wirtz, M. | | | |
Arabidopsis glutathione reductase 2 is indispensable in plastids, while mitochondrial glutathione is safeguarded by additional reduction and transport systems | Marty, L., Bausewein, D., Muller, C., Bangash, S.A.K., Moseler, A., Schwarzlander, M., Muller-Schussele, S.J., Zechmann, B., Riondet, C., Balk, J., Wirtz, M., Hell, R., Reichheld, J.P. & Meyer, A.J. | | New Phytol: 224, 1569-1584 | |
Differential N-end Rule Degradation of RIN4/NOI Fragments Generated by the AvrRpt2 Effector Protease | Goslin, K., Eschen-Lippold, L., Naumann, C., Linster, E., Sorel, M., Klecker, M., de Marchi, R., Kind, A., Wirtz, M., Lee, J., Dissmeyer, N. & Graciet, E. | | Plant Physiol: 180, 2272-2289 | |
Distribution of control in the sulfur assimilation in Arabidopsis thaliana depends on environmental conditions | Feldman-Salit, A., Veith, N., Wirtz, M., Hell, R. & Kummer, U. | | New Phytol: 222, 1392-1404 | |
SULTR3s Function in Chloroplast Sulfate Uptake and Affect ABA Biosynthesis and the Stress Response | Chen, Z., Zhao, P.-X., Miao, Z.-Q., Qi, G.-F., Wang, Z., Yuan, Y., Ahmad, N., Cao, M.-J., Hell, R., Wirtz, M. & Xiang, C.-B. | | Plant Physiol: 180, 593-604 | |
The Recovery from Sulfur Starvation Is Independent from the mRNA Degradation Initiation Enzyme PARN in Arabidopsis | Armbruster, L., Uslu, V.V., Wirtz, M. & Hell, R. | | | |
Sulfur Partitioning between Glutathione and Protein Synthesis Determines Plant Growth | Speiser, A., Silbermann, M., Dong, Y., Haberland, S., Uslu, V.V., Wang, S., Bangash, S.A.K., Reichelt, M., Meyer, A.J., Wirtz, M. & Hell, R. | | Plant Physiol: 177, 927-937 | |
N-terminal acetylation: an essential protein modification emerges as an important regulator of stress responses | | | | |
Chloroplast Acetyltransferase NSI Is Required for State Transitions in Arabidopsis thaliana | Koskela, M.M., Brunje, A., Ivanauskaite, A., Grabsztunowicz, M., Lassowskat, I., Neumann, U., Dinh, T.V., Sindlinger, J., Schwarzer, D., Wirtz, M., Tyystjarvi, E., Finkemeier, I. & Mulo, P. | | Plant Cell: 30, 1695-1709 | |
Sulfate is Incorporated into Cysteine to Trigger ABA Production and Stomatal Closure | Batool, S., Uslu, V.V., Rajab, H., Ahmad, N., Waadt, R., Geiger, D., Malagoli, M., Xiang, C.B., Hedrich, R., Rennenberg, H., Herschbach, C., Hell, R. & Wirtz, M. | | Plant Cell: 30, 2973-2987 | |
The redox-sensitive module of cyclophilin 20-3, 2-cysteine peroxiredoxin and cysteine synthase integrates sulfur metabolism and oxylipin signaling in the high light acclimation response | Mueller, S.M., Wang, S., Telman, W., Liebthal, M., Schnitzer, H., Viehhauser, A., Sticht, C., Delatorre, C., Wirtz, M., Hell, R. & Dietz, K.J. | | | |
Drought-Enhanced Xylem Sap Sulfate Closes Stomata by Affecting ALMT12 and Guard Cell ABA Synthesis | Malcheska, F., Ahmad, A., Batool, S., Müller, H.M., Ludwig-Müller, J., Kreuzwieser, J., Randewig, D., Hänsch, R., Mendel, R.R., Hell, R., Wirtz, M., Geiger, D., Ache, P., Hedrich, R., Herschbach, C. & Rennenberg, H. | | Plant Physiol: 174, 798-814 | |
The glyceraldehyde-3-phosphate dehydrogenase GapDH of Corynebacterium diphtheriae is redox-controlled by protein S-mycothiolation under oxidative stress | Hillion, M., Imber, M., Pedre, B., Bernhardt, J., Saleh, M., Loi, V.V., Maass, S., Becher, D., Astolfi Rosado, L., Adrian, L., Weise, C., Hell, R., Wirtz, M., Messens, J. & Antelmann, H. | | | |
Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress | Hillion, M., Bernhardt, J., Busche, T., Rossius, M., Maass, S., Becher, D., Rawat, M., Wirtz, M., Hell, R., Ruckert, C., Kalinowski, J. & Antelmann, H. | | | |
Apoplastic gamma-glutamyl transferase activity encoded by GGT1 and GGT2 is important for vegetative and generative development | Giaretta, S., Prasad, D., Forieri, I., Vamerali, T., Trentin, A.R., Wirtz, M., Hell, R. & Masi, A. | | Plant Physiol Biochem: 115, 44-56 | |
System analysis of metabolism and the transcriptome in Arabidopsis thaliana roots reveals differential co-regulation upon iron, sulfur and potassium deficiency | Forieri, I., Sticht, C., Reichelt, M., Gretz, N., Hawkesford, M.J., Malagoli, M., Wirtz, M. & Hell, R. | | Plant Cell Environ: 40, 95-107 | |
Integration of light and metabolic signals for stem cell activation at the shoot apical meristem | Pfeiffer, A., Janocha, D., Dong, Y., Medzihradszky, A., Schone, S., Daum, G., Suzaki, T., Forner, J., Langenecker, T., Rempel, E., Schmid, M., Wirtz, M., Hell, R. & Lohmann, J.U. | | | |
Nuclear Localised MORE SULPHUR ACCUMULATION1 Epigenetically Regulates Sulphur Homeostasis in Arabidopsis thaliana | Huang, X.Y., Chao, D.Y., Koprivova, A., Danku, J., Wirtz, M., Muller, S., Sandoval, F.J., Bauwe, H., Roje, S., Dilkes, B., Hell, R., Kopriva, S. & Salt, D.E. | | | |
Ectopically expressed glutaredoxin ROXY19 negatively regulates the detoxification pathway in Arabidopsis thaliana | Huang, L.J., Li, N., Thurow, C., Wirtz, M., Hell, R. & Gatz, C. | | | |
MTHFD1 controls DNA methylation in Arabidopsis | Groth, M., Moissiard, G., Wirtz, M., Wang, H., Garcia-Salinas, C., Ramos-Parra, P.A., Bischof, S., Feng, S., Cokus, S.J., John, A., Smith, D.C., Zhai, J., Hale, C.J., Long, J.A., Hell, R., Diaz de la Garza, R.I. & Jacobsen, S.E. | | | |
Drought stress in maize causes differential acclimation responses of glutathione and sulfur metabolism in leaves and roots | Ahmad, N., Malagoli, M., Wirtz, M. & Hell, R. | | | |
Relation between chemotaxis and consumption of amino acids in bacteria | Yang, Y., A, M.P., Hofler, C., Poschet, G., Wirtz, M., Hell, R. & Sourjik, V. | | Mol Microbiol: 96, 1272-1282 | |
Two N-terminal acetyltransferases antagonistically regulate the stability of a nod-like receptor in Arabidopsis | Xu, F., Huang, Y., Li, L., Gannon, P., Linster, E., Huber, M., Kapos, P., Bienvenut, W., Polevoda, B., Meinnel, T., Hell, R., Giglione, C., Zhang, Y., Wirtz, M., Chen, S. & Li, X. | | Plant Cell: 27, 1547-1562 | |
Mitochondrial Dihydrolipoyl Dehydrogenase Activity Shapes Photosynthesis and Photorespiration of Arabidopsis thaliana | Timm, S., Wittmiss, M., Gamlien, S., Ewald, R., Florian, A., Frank, M., Wirtz, M., Hell, R., Fernie, A.R. & Bauwe, H. | | Plant Cell: 27, 1968-1984 | |
Characterization of the serine acetyltransferase gene family of Vitis vinifera uncovers differences in regulation of OAS synthesis in woody plants | Tavares, S., Wirtz, M., Beier, M.P., Bogs, J., Hell, R. & Amancio, S. | | Frontiers in Plant Science: 6, 74 | |
The significance of cysteine synthesis for acclimation to high light conditions | Speiser, A., Haberland, S., Watanabe, M., Wirtz, M., Dietz, K.-J., Saito, K. & Hell, R. | | Frontiers in Plant Science: 5, 776 | |
Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in Arabidopsis | Linster, E., Stephan, I., Bienvenut, W.V., Maple-Grodem, J., Myklebust, L.M., Huber, M., Reichelt, M., Sticht, C., Geir Moller, S., Meinnel, T., Arnesen, T., Giglione, C., Hell, R. & Wirtz, M. | | | |
Molecular identification and functional characterization of the first Na-acetyltransferase in plastids by global acetylome profiling | Dinh, T.V., Bienvenut, W.V., Linster, E., Feldman-Salit, A., Jung, V.A., Meinnel, T., Hell, R., Giglione, C. & Wirtz, M. | | Proteomics: 15, 2426-2435 | |
Sulfide detoxification in plant mitochondria | Birke, H., Hildebrandt, T.M., Wirtz, M. & Hell, R. | | Methods in Enzymology: 555, 271-286 | |
The Role of Compartment-Specific Cysteine Synthesis for Sulfur Homeostasis During H2S Exposure in Arabidopsis | Birke, H., De Kok, L.J., Wirtz, M. & Hell, R. | | Plant & Cell Phys: 56, 358-367 | |
Affinity Purification of O-Acetylserine(thiol)lyase from Chlorella sorokiniana by Recombinant Proteins from Arabidopsis thaliana | Salbitani, G., Wirtz, M., Hell, R. & Carfagna, S. | | | |
Evidence for several cysteine transport mechanisms in the mitochondrial membranes of Arabidopsis thaliana | Lee, C.P., Wirtz, M. & Hell, R. | | Plant & Cell Phys: 55, 64-73 | |
The Mitochondrial Sulfur Dioxygenase ETHYLMALONIC ENCEPHALOPATHY PROTEIN1 Is Required for Amino Acid Catabolism during Carbohydrate Starvation and Embryo Development in Arabidopsis | Krüßel, L., Junemann, J., Wirtz, M., Birke, H., Thornton, J.D., Browning, L.W., Poschet, G., Hell, R., Balk, J., Braun, H.P. & Hildebrandt, T.M. | | Plant Physiol: 165, 92-104 | |
Sulfate availability affects ABA levels and germination response to ABA and salt stress in Arabidopsis thaliana | Cao, M.J., Wang, Z., Zhao, Q., Mao, J.L., Speiser, A., Wirtz, M., Hell, R., Zhu, J.K. & Xiang, C.B. | | | |
Methionine salvage and S-adenosylmethionine: essential links between sulfur, ethylene and polyamine biosynthesis | Sauter, M., Moffatt, B., Saechao, M.C., Hell, R. & Wirtz, M. | | | |
Toward new perspectives on the interaction of iron and sulfur metabolism in plants | Forieri, I., Wirtz, M. & Hell, R. | | Frontiers in Plant Science: 4, 357 | |
Balancing metabolites in drought: the sulfur assimilation conundrum | Chan, K.X., Wirtz, M., Phua, S.Y., Estavillo, G.M. & Pogson, B.J. | | Trends Plant Sci: 18, 18-29 | |
SULTR3;1 is a chloroplast-localized sulfate transporter in Arabidopsis thaliana | Cao, M.J., Wang, Z., Wirtz, M., Hell, R., Oliver, D.J. & Xiang, C.B. | | | |
Successful Fertilization Requires the Presence of at Least One Major O-Acetylserine(thiol)lyase for Cysteine Synthesis in Pollen of Arabidopsis | Birke, H., Heeg, C., Wirtz, M. & Hell, R. | | Plant Physiol: 163, 959-972 | |
Mitochondrial Cysteine Synthase Complex Regulates O-Acetylserine Biosynthesis in Plants | Wirtz, M., Beard, K.F.M., Lee, C.P., Boltz, A., Schwarzländer, M., Fuchs, C., Meyer, A.J., Heeg, C., Sweetlove, L.J., Ratcliffe, R.G. & Hell, R. | | J Biol Chem: 287, 27941-27947 | |
Recycling of methylthioadenosine is essential for normal vascular development and reproduction in Arabidopsis | Waduwara-Jayabahu, I., Oppermann, Y., Wirtz, M., Hull, Z.T., Schoor, S., Plotnikov, A.N., Hell, R., Sauter, M. & Moffatt, B.A. | | Plant Physiol: 158, 1728-1744 | |
Targeted Systems Biology Profiling of Tomato Fruit Reveals Coordination of the Yang Cycle and a Distinct Regulation of Ethylene Biosynthesis during Postclimacteric Ripening | Van de Poel, B., Bulens, I., Markoula, A., Hertog, M.L.A.T.M., Dreesen, R., Wirtz, M., Vandoninck, S., Oppermann, Y., Keulemans, J., Hell, R., Waelkens, E., De Proft, M.P., Sauter, M., Nicolai, B.M. & Geeraerd, A.H. | | Plant Physiol: 160, 1498-1514 | |
Selenate and molybdate alter sulfate transport and assimilation in Brassica juncea L. Czern.: Implications for phytoremediation | Schiavon, M., Pittarello, M., Pilon-Smits, E.A.H., Wirtz, M., Hell, R. & Malagoli, M. | | Environmental and Experimental Botany: 75, 41-51 | |
Transcriptome profiling of genes differentially modulated by sulfur and chromium identifies potential targets for phytoremediation and reveals a complex S-Cr interplay on sulfate transport regulation in B. juncea | Schiavon, M., Galla, G., Wirtz, M., Pilon-Smits, E.A., Telatin, V., Quaggiotti, S., Hell, R., Barcaccia, G. & Malagoli, M. | | J Hazard Mater: 239-240, 192-205 | |
Effects of fou8/fry1 Mutation on Sulfur Metabolism: Is Decreased Internal Sulfate the Trigger of Sulfate Starvation Response? | Lee, B.R., Huseby, S., Koprivova, A., Chetelat, A., Wirtz, M., Mugford, S.T., Navid, E., Brearley, C., Saha, S., Mithen, R., Hell, R., Farmer, E.E. & Kopriva, S. | | | |
Improved sulfur nutrition provides the basis for enhanced production of sulfur-containing defense compounds in Arabidopsis thaliana upon inoculation with Alternaria brassicicola | Kruse, C., Haas, F.H., Jost, R., Reiser, B., Reichelt, M., Wirtz, M., Gershenzon, J., Schnug, E. & Hell, R. | | J Plant Physiol: 169, 740-743 | |
Vacuolar nicotianamine has critical and distinct roles under iron deficiency and for zinc sequestration in Arabidopsis | Haydon, M.J., Kawachi, M., Wirtz, M., Hillmer, S., Hell, R. & Kramer, U. | | | |
Allosterically gated enzyme dynamics in the cysteine synthase complex regulate cysteine biosynthesis in Arabidopsis thaliana | Feldman-Salit, A., Wirtz, M., Lenherr, E.D., Throm, C., Hothorn, M., Scheffzek, K., Hell, R. & Wade, R.C. | | | |
The relevance of compartmentation for cysteine synthesis in phototrophic organisms | Birke, H., Muller, S.J., Rother, M., Zimmer, A.D., Hoernstein, S.N., Wesenberg, D., Wirtz, M., Krauss, G.J., Reski, R. & Hell, R. | | Protoplasma: 249 Suppl 2, 147-155 | |
Cysteine biosynthesis, in concert with a novel mechanism, contributes to sulfide detoxification in mitochondria of Arabidopsis thaliana | Birke, H., Haas, F.H., De Kok, L.J., Balk, J., Wirtz, M. & Hell, R. | | | |
Generation of Se-fortified broccoli as functional food: impact of Se fertilization on S metabolism | Hsu, F.C., Wirtz, M., Heppel, S.C., Bogs, J., Kramer, U., Khan, M.S., Bub, A., Hell, R. & Rausch, T. | | Plant Cell Environ: 34, 192-207 | |
Molecular Biology, Biochemistry and Cellular Physiology of Cysteine Metabolism in Arabidopsis thaliana | | | The Arabidopsis Book: 9, e0154 | |
Evidence for a SAL1-PAP Chloroplast Retrograde Pathway That Functions in Drought and High Light Signaling in Arabidopsis | Estavillo, G.M., Crisp, P.A., Pornsiriwong, W., Wirtz, M., Collinge, D., Carrie, C., Giraud, E., Whelan, J., David, P., Javot, H., Brearley, C., Hell, R., Marin, E. & Pogson, B.J. | | Plant Cell: 23, 3992-4012 | |
Sultr4;1 mutant seeds of Arabidopsis have an enhanced sulphate content and modified proteome suggesting metabolic adaptations to altered sulphate compartmentalization | Zuber, H., Davidian, J.-C., Wirtz, M., Hell, R., Belghazi, M., Thompson, R. & Gallardo, K. | | Bmc Plant Biology: 10, 78 | |
The Seed Composition of Arabidopsis Mutants for the Group 3 Sulfate Transporters Indicates a Role in Sulfate Translocation within Developing Seeds | Zuber, H., Davidian, J.-C., Aubert, G., Aime, D., Belghazi, M., Lugan, R., Heintz, D., Wirtz, M., Hell, R., Thompson, R. & Gallardo, K. | | Plant Physiol: 154, 913-926 | |
Enzymes of cysteine synthesis show extensive and conserved modifications patterns that include N-alpha-terminal acetylation | Wirtz, M., Heeg, C., Samami, A.A., Ruppert, T. & Hell, R. | | Amino Acids: 39, 1077-1086 | |
Structure and function of the hetero-oligomeric cysteine synthase complex in plants | Wirtz, M., Birke, H., Heeg, C., Mueller, C., Hosp, F., Throm, C., Koenig, S., Feldman-Salit, A., Rippe, K., Petersen, G., Wade, R.C., Rybin, V., Scheffzek, K. & Hell, R. | | J Biol Chem: 285, 32810-32817 | |
Overexpression of serine acetlytransferase produced large increases in O-acetylserine and free cysteine in developing seeds of a grain legume | Tabe, L., Wirtz, M., Molvig, L., Droux, M. & Hell, R. | | | |
Sulfite Reductase Defines a Newly Discovered Bottleneck for Assimilatory Sulfate Reduction and Is Essential for Growth and Development in Arabidopsis thaliana | Khan, M.S., Haas, F.H., Allboje Samami, A., Moghaddas Gholami, A., Bauer, A., Fellenberg, K., Reichelt, M., Hansch, R., Mendel, R.R., Meyer, A.J., Wirtz, M. & Hell, R. | | Plant Cell: 22, 1216-1231 | |
'Inhibition of 5''-methylthioadenosine metabolism in the Yang cycle alters polyamine levels, and impairs seedling growth and reproduction in Arabidopsis ' | Burstenbinder, K., Waduwara, I., Schoor, S., Moffatt, B.A., Wirtz, M., Minocha, S.C., Oppermann, Y., Bouchereau, A., Hell, R. & Sauter, M. | | | |
SAM levels, gene expression of SAM synthetase, methionine synthase and ACC oxidase, and ethylene emission from N. suaveolens flowers | Roeder, S., Dreschler, K., Wirtz, M., Cristescu, S.M., van Harren, F.J., Hell, R. & Piechulla, B. | | Plant Mol Biol: 70, 535-546 | |
'Disruption of Adenosine-5''-Phosphosulfate Kinase in Arabidopsis Reduces Levels of Sulfated Secondary Metabolites ' | Mugford, S.G., Yoshimoto, N., Reichelt, M., Wirtz, M., Hill, L., Mugford, S.T., Nakazato, Y., Noji, M., Takahashi, H., Kramell, R., Gigolashvili, T., Flugge, U.-I., Wasternack, C., Gershenzon, J., Hell, R., Saito, K. & Kopriva, S. | | | |
The NADPH-dependent thioredoxin system constitutes a functional backup for cytosolic glutathione reductase in Arabidopsis | Marty, L., Siala, W., Schwarzlander, M., Fricker, M.D., Wirtz, M., Sweetlove, L.J., Meyer, Y., Meyer, A.J., Reichheld, J.-P. & Hell, R. | | Proc Natl Acad Sci U S A 106, 9109-9114 | |
The analysis of Arabidopsis nicotianamine synthase mutants reveals functions for nicotianamine in seed iron loading and iron deficiency responses | Klatte, M., Schuler, M., Wirtz, M., Fink-Straube, C., Hell, R. & Bauer, P. | | Plant Physiol: 150, 257-271 | |
A Mechanistic Model of the Cysteine Synthase Complex | Feldman-Salit, A., Wirtz, M., Hell, R. & Wade, R.C. | | | |
Dynamic plastid redox signals integrate gene expression and metabolism to induce distinct metabolic states in photosynthetic acclimation in Arabidopsis | Brautigam, K., Dietzel, L., Kleine, T., Stroher, E., Wormuth, D., Dietz, K.J., Radke, D., Wirtz, M., Hell, R., Dormann, P., Nunes-Nesi, A., Schauer, N., Fernie, A.R., Oliver, S.N., Geigenberger, P., Leister, D. & Pfannschmidt, T. | | Plant Cell: 21, 2715-2732 | |
Interactions between chromium and sulfur metabolism in Brassica juncea | Schiavon, M., Pilon-Smits, E.A., Wirtz, M., Hell, R. & Malagoli, M. | | J Environ Qual: 37, 1536-1545 | |
Differential Regulation of the Expression of Two High-Affinity Sulfate Transporters, SULTR1.1 and SULTR1.2 in Arabidopsis | Rouached, H., Wirtz, M., Alary, R., Hell, R., Arpat, A.B., Davidian, J.-C.E., Fourcroy, P. & Berthomieu, P. | | Plant Physiol: 147, 897-911 | |
Restricting glutathione biosynthesis to the cytosol is sufficient for normal plant development | Pasternak, M., Lim, B., Wirtz, M., Hell, R., Cobbett, C.S. & Meyer, A.J. | | | |
Analysis of the Arabidopsis O-acetylserine(thiol)lyase gene family demonstrates compartment-specific differences in the regulation of cysteine synthesis | Heeg, C., Kruse, C., Jost, R., Gutensohn, M., Ruppert, T., Wirtz, M. & Hell, R. | | | |
Mitochondrial serine acetyltransferase functions as a pacemaker of cysteine synthesis in plant cells | Haas, F.H., Heeg, C., Queiroz, R., Bauer, A., Wirtz, M. & Hell, R. | | Plant Physiol: 148, 1055-1067 | |
Dominant-negative modification reveals the regulatory function of the multimeric cysteine synthase protein complex in transgenic tobacco | | | | |
The role of cellular compartmentation for sulfur amino acid biosynthesis | | | | |
Chromate differentially affects the expression of a high-affinity sulfate transporter and isoforms of components of the sulfate assimilatory pathway in Zea mays (L.). | Schiavon, M., Wirtz, M., Borsa, P., Quaggiotti, S., Hell, R. & Malagoli, M. | | | |
'OsMTN encodes a 5''-methylthioadenosine nucleosidase that is up-regulated during submergence-induced ethylene synthesis in rice (Oryza sativa L.) ' | Rzewuski, G., Cornell, K.A., Rooney, L., Burstenbinder, K., Wirtz, M., Hell, R. & Sauter, M. | | | |
Sulphite oxidase as key enzyme for protecting plants against sulphur dioxide | Lang, C., Popko, J., Wirtz, M., Hell, R., Herschbach, C., Kreuzwieser, J., Rennenberg, H., Mendel, R.R. & Hansch, R. | | Plant Cell Environ: 30, 447-455 | |
The role of methionine recycling for ethylene synthesis in Arabidopsis | Burstenbinder, K., Rzewuski, G., Wirtz, M., Hell, R. & Sauter, M. | | | |
Functional analysis of the cysteine synthase protein complex from plants: structural, biochemical and regulatory properties. | | | J Plant Physiol: 163, 273-286 | |
Synthesis of the sulfur amino acids: cysteine and methionine | | | Photosynthesis Research: 86, 345-362 | |
Expression profiling of metabolic genes in response to methyl jasmonate reveals regulation of genes of primary and secondary sulfur-related pathways in Arabidopsis thaliana | Jost, R., Altschmied, L., Bloem, E., Bogs, J., Gershenzon, J., Hähnel, U., Hänsch, R., Hartmann, T., Kopriva, S., Kruse, C., Mendel, R., Papenbrock, J., Reichelt, M., Rennenberg, H., Schnug, E., Schmidt, A., Textor, S., Tokuhisa, J., Wachter, A., Wirtz, M., Rausch, T. & Hell, R. | | Photosynthesis Research: 86, 491-508 | |
Retrograde plastid redox signals in the expression of nuclear genes for chloroplast proteins of Arabidopsis thaliana | Fey, V., Wagner, R., Brautigam, K., Wirtz, M., Hell, R., Dietzmann, A., Leister, D., Oelmuller, R. & Pfannschmidt, T. | | J Biol Chem: 280, 5318-5328 | |
O-acetylserine (thiol) lyase: an enigmatic enzyme of plant cysteine biosynthesis revisited in Arabidopsis thaliana | Wirtz, M., Droux, M. & Hell, R. | | | |
Regulation of sulphate assimilation by glutathione in poplars (Populus tremula x P. alba) of wild type and overexpressing g-glutamylcysteine synthetase in the cytosol | Hartmann, T., Honicke, P., Wirtz, M., Hell, R., Rennenberg, H. & Kopriva, S. | | | |
Regulation of sulfate uptake and expression of sulfate transporter genes in Brassica oleracea as affected by atmospheric H2S and pedospheric sulfate nutrition | Buchner, P., Stuiver, C.E.E., Westerman, S., Wirtz, M., Hell, R., Hawkesford, M.J. & De Kok, L.J. | | Plant Physiol: 136, 3396-3408 | |
Production of cysteine for bacterial and plant biotechnology: Application of cysteine feedback-insensitive isoforms of serine acetyltransferase | | | | |
Molecular and biochemical analysis of the enzymes of cysteine biosynthesis in the plant Arabidopsis thaliana | Hell, R., Jost, R., Berkowitz, O. & Wirtz, M. | | | |
Use of biomolecular interaction analysis to elucidate the regulatory mechanism of the cysteine synthase complex from Arabidopsis thaliana | Berkowitz, O., Wirtz, M., Wolf, A., Kuhlmann, J. & Hell, R. | | J Biol Chem: 277, 30629-30634 | |
The cysteine synthase complex from plants - Mitochondrial serine acetyltransferase from Arabidopsis thaliana carries a bifunctional domain for catalysis and protein-protein interaction | Wirtz, M., Berkowitz, O., Droux, M. & Hell, R. | | European Journal of Biochemistry: 268, 686-693 | |
Genomic and functional characterization of the oas gene family encoding O-acetylserine (thiol) lyases, enzymes catalyzing the final step in cysteine biosynthesis in Arabidopsis thaliana | Jost, R., Berkowitz, O., Wirtz, M., Hopkins, L., Hawkesford, M.J. & Hell, R. | | | |
